Probiotics for Health Benefits: The Regulatory Concerns and Suggestive Roadmap
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 5
Abstract
Probiotics, the friendly bugs, has gained impressive attention worldwide due to their nutraceutical and pharmaceutical benefits, established in recent years. However existing regulatory regime in various countries has ambiguities regarding its classification based on intended use and respective approval process. Author and his coworkers have proposed a revised definition and categorization of probiotic products along with possible path to develop a comprehensive guideline for global enactment. Probiotics, as defined by FAO/WHO, are live microorganisms, which when administered in adequate amounts confer a health benefit on the host. In recent days, use of probiotics for health benefits has increased due to their wide range of medicinal values complemented with low cost and insignificant side effects. This has resulted in commercial exploration of probiotics globally for nutraceutical and pharmaceutical applications. The major driving force behind the success of these products is growing interest in the concept of holistic health through diet regulation as preventive step to avoid various diseases. In last two decades, probiotics are also reported to be useful in treatment of some serious clinical disorders such as cancer, diabetes, cardiovascular diseases, bacterial vaginosis, urinary tract infections, allergic diseases (atopic dermatitis, allergic rhinitis) and prevention of dental caries, respiratory infections, lactose intolerance, variety of gastrointestinal disorders like diarrhea, irritable bowel syndrome etc. Recent findings have established that some of the probiotic strains may have therapeutic potential and involvement in new therapeutic pathways in dysbiosis related diseases. The frequent and sometimes irrational use of antibiotics has also made probiotics as almost essential component of prescription specially to maintain the friendly microbial flora in gut and intestines. Ever increasing incidences of gastrointestinal diseases, market acceptance and emerging biotechnological advancements in formulation designing also resulted in expansion of probiotic market across the globe. The probiotic market is presently growing at a CAGR of 6.8% with an expected market value of USD 45 billion in 2018 attributed to food, beverage, dietary supplements and pharmaceuticals.
Authors and Affiliations
Ashish Baldi
Keywords
Related Articles
- EP ID EP569512
- DOI 10.26717/BJSTR.2017.01.000405
- Views 172
- Downloads 0
Cerebrospinal Fluid Lactate Concentration to Differentiate Bacterial from Viral Meningitis in Children
Objective: To define an optimal CSF lactate concentration that can be called significant for the differentiation bacterial meningitis from viral meningitis in children. Methods: Children with clinical findings compatible...
A Spatial Crypto Technique for Secure Data Transmission
his paper presents a spatial encryption technique for secured transmission of data in networks. The algorithm is designed to break the ciphered data packets into multiple data which are to be packaged into a spatial temp...
FC for Relapsed/Refractory Diffuse Large B Cell Lymphoma
Despite overall improvements, relapsed/refractory diffuse large B-cell lymphoma (DLBCL)remains a major cause of morbidity [1]. Treatment option for relapsed/refractory DLBCL is salvage chemotherapy followed by an autolog...
Robotic-Assisted Transanal Surgery for Rectal Schwannoma: A case report
Aim: The aim of this stud was to present a case with uncommon rectal schwannoma undergoing robotic transanal surgery. Background: Gastrointestinal schwannomas are uncommon and in particular, rectal schwannomas are even r...
Premorbid Cognitive Dysfunction and Endophenotypes in Bipolar Disorder: A Rapid Review
On the contrary that happened with schizophrenia, it has not been completely clarify if cognitive alterations precede the illness or are a consequence of it. Although some data indicate that some cognitive deficits are a...