Probiotics for Health Benefits: The Regulatory Concerns and Suggestive Roadmap
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 5
Abstract
Probiotics, the friendly bugs, has gained impressive attention worldwide due to their nutraceutical and pharmaceutical benefits, established in recent years. However existing regulatory regime in various countries has ambiguities regarding its classification based on intended use and respective approval process. Author and his coworkers have proposed a revised definition and categorization of probiotic products along with possible path to develop a comprehensive guideline for global enactment. Probiotics, as defined by FAO/WHO, are live microorganisms, which when administered in adequate amounts confer a health benefit on the host. In recent days, use of probiotics for health benefits has increased due to their wide range of medicinal values complemented with low cost and insignificant side effects. This has resulted in commercial exploration of probiotics globally for nutraceutical and pharmaceutical applications. The major driving force behind the success of these products is growing interest in the concept of holistic health through diet regulation as preventive step to avoid various diseases. In last two decades, probiotics are also reported to be useful in treatment of some serious clinical disorders such as cancer, diabetes, cardiovascular diseases, bacterial vaginosis, urinary tract infections, allergic diseases (atopic dermatitis, allergic rhinitis) and prevention of dental caries, respiratory infections, lactose intolerance, variety of gastrointestinal disorders like diarrhea, irritable bowel syndrome etc. Recent findings have established that some of the probiotic strains may have therapeutic potential and involvement in new therapeutic pathways in dysbiosis related diseases. The frequent and sometimes irrational use of antibiotics has also made probiotics as almost essential component of prescription specially to maintain the friendly microbial flora in gut and intestines. Ever increasing incidences of gastrointestinal diseases, market acceptance and emerging biotechnological advancements in formulation designing also resulted in expansion of probiotic market across the globe. The probiotic market is presently growing at a CAGR of 6.8% with an expected market value of USD 45 billion in 2018 attributed to food, beverage, dietary supplements and pharmaceuticals.
Authors and Affiliations
Ashish Baldi
Keywords
Related Articles
- EP ID EP569512
- DOI 10.26717/BJSTR.2017.01.000405
- Views 182
- Downloads 0
Monthly Variation in Finnish Total Mortality During 1891-2017, Temperature and Discussions
Seasonal variation in mortality resulting from cardiovascular diseases (CVD) have been demonstrated e.g. in Norway and Ireland, with the highest levels observed during the coldest months of the yea...
Association of Variables as Markers for the Classification of Accessions of the Cuban Cocoyam Collection Xanthosoma spp. (Araceae)
The present work was carried out on the basis of the previously obtained results where a total of 71 accessions of the Cuban cocoyam collection of the genus Xanthosoma in Cuba were used, which were characterized through...
Pediatric Pes Planus: A Review
Flat foot is a complex three-dimensional skeletal disorder with multifactorial etiology frequently encountered in evolutionary age, and tends to resolve spontaneously in adolescence. Despite the high frequency, there is...
Severe Obstetric Morbidity (Near miss)
Background: A case of “Near miss maternal” or severe obstetric condition is defined as the patient at risk of dying, which survives the complication that occurred during pregnancy, delivery or at the end of the puerperiu...
Beta-Ketothiolase Deficiency as A Treatable Neurometabolic Disorder: A Case Report Due to A Novel Compound Heterozygote Mutations in ACAT1 Gene
Mitochondrial 2-methylacetoacetyl-CoA thiolase deficiency (OMIM#203750, *607809) is a rare inherited disorder of isoleucine amino acid catabolism and ketone body metabolism. Clinical manifestations of this disorder a...