Production, Characterization and Clinical Applications of Third-generation Cephalosporins
Journal Title: Scholars Academic Journal of Biosciences - Year 2017, Vol 5, Issue 5
Abstract
Cephalosporin is one of most widely used drug in world wide. Cephalosporin mechanism of action is more resistant to other agents that have infections from these agents. Its classification ranking 4th generation cephalosporin is more critical than 3rd generation cephalosporin but both are critical in WHO criteria. In human medicines and all risk management factors used cephalosporin antibiotic as one of the major factor. Its production on large scale is very important. Cephalosporin produced from Cephalosporium acremonium which immobilized in agar or other agents and cephalosporin antibiotics produced under optimum and favorable conditions. Calcium alginate and glass wool also used for immobilization and repeated batch of shake flask fermentations used for its production. It was recently improved for the treatment of community acquired pneumonia. It has also broad spectrum activity against gram positive and gram negative bacteria. It is also used for the treatment of hospitalized patients. Cephalosporin shows low resistance ratio and safety measurements. It is mostly used for the treatment of skin complicated infections. It will evaluate the pharmacological characters, efficacy, safety, antimicrobial property and its application of cephalosporin in the treatment of community acquired pneumonia.
Authors and Affiliations
Hira Sundus, Kadija tul kubra, Manam Walait, Sikander Ali
Keywords
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