Progress in heatstroke-induced multiple organ damage
Journal Title: Perioperative Precision Medicine - Year 2024, Vol 2, Issue 3
Abstract
Heatstroke is a life-threatening acute condition characterized by dysregulated temperature control, resulting in high core temperature and multi-organ dysfunction. Despite extensive research, the molecular mechanisms underlying heatstroke-induced organ damage have not been fully elucidated. This review aims to summarize recent advancements in the field of heatstroke, focusing on etiological factors, organ damage, and molecular mechanisms. By exploring the intricate interplay between heat-related cytotoxicity, inflammatory response, and tissue dysfunction, this review offers insights for future research and clinical practice in managing heatstroke patients. Further investigations are warranted to elucidate the specific mechanisms of organ damage and improve treatment strategies for heatstroke.
Authors and Affiliations
Ruilong Li, Dezhi Guo, Tianying Li, Panpan Hu, Tianying Xu
Keywords
Related Articles
- EP ID EP750287
- DOI 10.61189/313377zqjuff
- Views 21
- Downloads 0
Progress in heatstroke-induced multiple organ damage
Heatstroke is a life-threatening acute condition characterized by dysregulated temperature control, resulting in high core temperature and multi-organ dysfunction. Despite extensive research, the molecular mechanisms und...
The interaction of Candida albicans with C-type lectin receptors
Candida albicans (C. albicans) is a ubiquitous commensal in the mammalian flora and the most prevalent fungal pathogen of humans. As an opportunistic fungus, C. albicans can cause mucosal and invasive infections. Invasiv...
Research progress of oxidative stress in sepsis-associated liver injury
Sepsis is a systemic inflammatory response that caused by infection or trauma, often resulting in multiple organ dysfunction. Its mortality rate is relatively high, ranging between 54% and 68%, and ineffective treatment...
Progress of artificial intelligence in anesthesia and perioperative medicine
Perioperative medicine is a series of medical activities throughout the perioperative period, including preoperative optimization, intraoperative safety, postoperative rehabilitation, and other activities. Anesthesia is...
Research advances in understanding the role and mechanism of pyroptosis in myocardial ischemia-reperfusion injury
Myocardial ischemia-reperfusion injury (MIRI) emerges when the restoration of blood flow fails to recover myocardial function following transient ischemia, marking a significant pathological challenge that adversely affe...