Pterygium: Clinical and Histopathological Study in Bundelkhand.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 6
Abstract
Purpose: is to study various Clinical aspects and Histopathological features ofpterygium. Pterygium represents a triangular conjunctivo–epithelial overgrowth, proliferating from the bulbar conjunctiva and covering the cornea, causing severe vision loss. It is an abnormal growth and differentiation of the conjunctival epithelial structures of the corneal limbus. Chronic exposures to solar ultraviolet radiation, heat and dust as the most common pathogenic entities involved in its evolution. Recent studies linked pterygium with neoplastic proliferation, as ocular limbic stem cells and p53-protein expression are altered. Materialsand Methods: Our study was conducted on 30 patients diagnosed with pterygium they were first clinically examined and their specimen , collected after surgery following admission of patients between February 2017 and April 2017 in the Departments of Ophthalmology of MLB Medical College Jhansi.Then histolopathological studies were performed on these specimens.Results: 60% patients were male,80% in the agegroup 31-35years,in 75% most common site being nasal and in 60% most common presentation being visual impairment. Histopathology showed the presence of a conjunctivo–epithelial structure, significantly different from the structure from which it developed.In 30% of the cases, the covering epithelium was similar to that of the bulbar conjunctival mucosa. In some cases, the appearance of the covering epithelium of the membrane appeared pleomorphic, with dysplastic aspects, suggesting significant alteration of cell proliferation and differentiation. In approximately 70% of patients, we identified goblet cells in the surface epithelium. They appeared either isolated or associated in variable numbers, structures resembling intraepithelial glands. Conclusions this study shows pterygium in both gender,age,its site,common presentation. And on histopathological examination significant changes both in the epithelium and in the underlying connective tissue were seen.
Authors and Affiliations
Dr. Renu Sahay, Dr. Jitendra Kumar, Dr. Jyoti Sharma
Keywords
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- EP ID EP600501
- DOI 10.9790/0853-16060116119.
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