Radiological and Histopathological Spectrum of CNS Tumors in Tertiary Care Centre: A Retrospective and Prospective Study
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2019, Vol 8, Issue 4
Abstract
Background: To study the spectrum of CNS tumors in different age groups, locations, clinical presentations, their radiological and histo-pathological profile in local population of Kanpur. Methods: This study includes 119 radiologicaly diagnosed and operated cases of CNS tumors, registered between Sept. 2014 to Aug. 2017 in Pathology Department, RMCH and RC and various other hospitals, Kanpur and classified according to WHO 2007 classification along with grading (WHO Gr.I to Gr.IV) of tumors. Results: A wide range of histopathological spectrum of CNS tumors was observed. Overall tumors of neuroepithelial tissue (47.9%) was the most common entity followed by tumors of meninges (25.2%), cranial and spinal cord nerves (19.3%), metastatic tumors (4.2%), tumors of sellar region (1.7%) and lymphomas (1.7%). The most common CNS tumors found in childhood (1st and 2nd decade) were ependymoma (5.04%), low grade astrocytoma (3.36%) and medulloblastoma (1.68%). In adults (3rd to 6th decade) astrocytic tumors (21.0%) comprise the most common group followed by meningiomas (16.8%). While in elderly (>60 years) astrocytomas (10.1%) were most common followed by meningiomas (6.7%). Out of 119 cases, 80 (67.2%) were supratentorial, 24 (20.2%) infratentorial and 15 (12.6%) spinal. Most common presenting symptom in supratentorial tumors were headache (67.22%), seizure (47.89%) and motor weakness (37.81%) while in CPA tumors hearing loss and ataxia were the most common symptoms. Spinal tumors mainly presented with motor weakness and urinary symptom. Conclusions: Frequency of CNS tumors in local population in different age groups was found to be similar to studies conducted in different parts of India.
Authors and Affiliations
Babita Gupta
Keywords
Related Articles
- EP ID EP670214
- DOI 10.21088/ijprp.2278.14810.8519.5
- Views 63
- Downloads 0
Do Learning Styles Influence Learning Outcome in Pathology
Identifying and employing appropriate learning styles could play an important role in selecting teaching styles, which can improve education ultimately.The present study aimed to assess the diversity of learning styles a...
Bilateral Breast Involvement in Rosai-Dorfman Disease: Report of a Case in a Middle Aged Lady
A woman aged 40 years sought medical attention for bilateral breast swellings considered to be bilateral fibroadenomata or malignancy. Excised lump revealed to be Rosai-Dorfman disease with characteristic histology. Its...
Reproducibility of Modified Gleason Scoring System and Grade Group in Prostate Carcinoma on Microphotographs
Background: Pathologists can quickly transmit the microscopic images photographed in a certain location to remote centers for analyzing the images. Gleason scoring system forms an important prognostic parameter for thera...
Seroprevalence of Hepatitis C antibody in Blood Donors
Introduction: India has high prevalence of HCV in blood donors, which is easily transmitted through infected blood. The aim of the present study is to determine the seroprevalence of HCV in 14727 blood donors in Davanger...
Histomorphological Pattern of Lesions in Nephrectomy Specimen
Background: Nephrectomy is a common urological procedure in urological practice. It is indicated in patients presenting with a wide range of clinical conditions ranging from symptomatic chronic infections, obstruction, c...