Renal artery stenosis of the transplanted kidney as a cause of posttransplant arterial hypertensionRenal artery stenosis of the transplanted kidney as a cause of posttransplant arterial hypertension
Journal Title: Postępy Nauk Medycznych - Year 2014, Vol 27, Issue 2
Abstract
Hypertension after kidney transplantation is a very common disease and its etiology is usually complex. One of the causes of hypertension after kidney transplantation is transplanted renal artery stenosis (TRAS). The clinical features of TRAS include new-onset and refractory hypertension, allograft dysfunction especially after treatment with ACE inhibitor or AT1blockers, presence of bruit over the graft or arteriosclerosis in other arteries. It should be stressed that TRAS may be also completely asymptomatic. TRAS increases the risk of graft loss, including the patient’s death, almost three-fold. Colour Doppler Ultrasonography is the most common, non-invasive, screening method used for the detection of TRAS. Percutaneous transluminal renal angioplasty (PTRA) with stenting is the treatment of choice and restores kidney perfusion in 65-100% of cases. TRAS should be taken into consideration in every case of hypertension in patients after organ transplantation. Early detection and treatment improve function and survival of transplanted kidney and survival of patients.
Authors and Affiliations
Natalia Słabiak-Błaż, Teresa Nieszporek, Andrzej Więcek
Keywords
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