Role of Glycosylated Haemoglobin in Microvascular Complications in Type 2 Diabetes Mellitus
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 2
Abstract
Background: Diabetes mellitus is one of the most common chronic diseases in nearly all countries, and continues to increase in numbers and significance, as changing lifestyles lead to reduced physical activity, and increased obesity. Materials and Methods: The study included 100 type 2 diabetes mellitus patients. The patients were divided into 2 groups of 50 each. In group1, cases were type 2 diabetic patients without microvascular complications and in group 2, type 2 diabetic patients were with microvascular complications. These patients underwent various clinical tests like Urine analysis (for evaluation of U. Albumin), blood sampling (for complete haemogram, plasma glucose, HbA1c, Renal function tests). Results: Mean Fasting, post-prandial blood sugar level, HbA1c, Urine albumin, blood urea and serum creatinine among test group was significantly more than control group. Among test group, 48 patients had nephropathy, 19 patients had neuropathy and 34 patients had retinopathy. Conclusion: HbA1c provides a reliable measure of chronic glycemia and correlates well with the risk of long term diabetic complications so that it is currently considered the test of choice for monitoring and chronic management of diabetes. However, the cut point of HbA1c from the diagnostic point of view is still controversial.
Authors and Affiliations
Deepika Puri, Anuradha R Gawarle, Ritu Adhana
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