Role of Imprint cytology in rapid diagnosis of ovarian neoplasms with histopathology correlation
Journal Title: International Archives of Integrated Medicine - Year 2018, Vol 5, Issue 11
Abstract
Background: Imprint cytology plays a major role in rapid intraoperative diagnosis of lesions similar to frozen sections. Besides its speed and simplicity, it also provides excellent cellular details. Although histopathology is considered to be gold standard in diagnosis of ovarian neoplasms, yet the delay involved may at times affect the course of treatment. The optimal management of benign and malignant ovarian neoplasms is different especially in patients who want to retain fertility. This calls for a rapid intraoperative diagnosis which will decide further management. Aim and objectives: To study the imprint cytology of ovarian neoplasms and compare with histopathology findings, to establish the reliability of imprint smears in intraoperative diagnosis by statistical evaluation. Material and methods: The present study was done at MNJ Institute of Oncology, Hyderabad, a tertiary care center for period of one and half years i.e. from January 2017 to June 2018. The study was done on 40 fresh unfixed ovarian specimens sent for imprint cytology. Multiple imprint smears was taken from fresh resected masses after detailed gross examination. The findings were noted and compared to subsequent histopathology sections. Results: In the present study, out of 40 cases, 21 (52.5%) were benign, 9(22.5%) were borderline, 10(25%) were malignant based on imprint cytology smears. On histopathology sections, 22 (55%) were benign, 1(2.5%) was borderline and 17(42.5%) were malignant. The overall accuracy was 87.5% on imprint smears. Conclusion: Imprint cytology is an excellent, simple, inexpensive, useful diagnostic tool in intraoperative diagnosis of ovarian neoplasms. This forms an important step in intraoperative decision-making for better management.
Authors and Affiliations
Annapoorna Sireesha, B Triveni, Sangeeta Parmer, K Srilaxmi, Sai Mallikarjun
Keywords
Related Articles
- EP ID EP416237
- DOI -
- Views 117
- Downloads 0
MRI is the gold standard investigation for early detection, extent of involvement and management of patient in Pott’s spine
Introduction: Tuberculosis is increasing in the developing countries and re-emerging in the developed ones because of overcrowding and increase in of population. Spinal TB is the most clinically important form of extra-p...
The role of prophylactic central compartment lymph node dissection in differentiated thyroid carcinoma
Background: Differentiated thyroid carcinoma, arising from thyroid follicular epithelial cells, accounts for the vast majority of thyroid carcinomas. Of the differentiated cancers, papillary cancer comprises about 85% of...
Role of MRI spine in evaluation of cases of neurotrophic arthropathy
Introduction: A neurotrophic joint (also known as a Charcot joint) refers to a progressive degenerative/ destructive joint disorder in patients with abnormal pain sensation and proprioception. A substantial number of neu...
Leuprolide Vs triptorelin: The recent trends in GnRH analogues in precocious puberty
Precocious puberty resulting from hypothalamic-pitiutary-gonadal axis activation is increasing problem in children and early institution of therapy for the axis suppression allows the patients to attain target adult heig...
Functional and radiological outcome in non-operative versus operative management of fracture clavicle
Background: Clavicle fractures are one of the most common bone injuries seen in adult population. Generally all the fracture clavicles were treated non-surgically by figure-eight bandage and surgical intervention like pl...