Role of intravenous paracetamol as an adjunct to epidural analgesia in immediate postoperative period in abdominal cancer surgeries
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 1
Abstract
Aims and Objectives: To evaluate analgesic efficacy and side effects of intravenous paracetamol, also assess IV-PCA morphine consumption in patients undertaken abdominal cancer surgery. Materials and Methods: Total 160 ASA grade I and II patients of both the sex, between age 18-70 years were randomly divided in two equal groups to receive either IV paracetamol 1gm or no paracetamol after surgery. Hemodynamic parameters, pain intensity scores, amount of morphine consumption and side effects were recorded. Results: The control group had higher mean heart rate, mean arterial blood pressures, mean respiratory rate than paracetamol group. Pain intensity score was much higher in control group at any time which needed considerably higher dose of rescue analgesic (IV morphine) for pain control than paracetamol group. We found no significant difference statistically in sedation scores in patients using patient controlled analgesia in either group. Side effects were found to be lower in paracetamol group compared to control group but difference was not significant statistically. Conclusion: Paracetamol is safe and effective drug for postoperative analgesia with negligible side effects.
Authors and Affiliations
Navnath K. Sonale, Devanand B. Pawar
Keywords
Related Articles
- EP ID EP472283
- DOI 10.18231/2394-4994.2018.0005
- Views 83
- Downloads 0
Anaesthetic management of an Extremely Low Birth Weight (ELBW) neonate with multiple co-morbidities
Anaesthetic management of an extremely low birth weight (ELBW) neonate is always a challenge. Challenges are substantial beginning from pre-operative preparation till the neonate has been shifted to the neonatal intensiv...
Comparison between dexmedetomidine and propofol for sedation during mechanically ventilated patients after major intraabdominal surgeries: An observational study
Introduction Major complex intraabdominal surgeries which have prolonged intraoperative surgical duration and wide hemodynamic fluctuations so they required an elective mechanical ventilation in view of large fluid shift...
Comparison of oxygenation and ventilation parameters between proseal laryngeal mask airway and endotracheal tube in patients undergoing laparoscopic surgeries: a prospective observational study
Introduction Use of endotracheal tube ETT has many limitations There is a need for an airway device with similar safety and good side effect profile In this prospective observational study the oxygenation and ventilation...
A clinical comparative study of 0.2% levobupivacaine with 25 mcg fentanyl versus 0.2% ropivacaine with 25 mcg fentanyl for post-operative epidural analgesia in patients undergoing lower limb orthopaedic surgeries
Objectives The objectives of our study were to compare the efficacy and safety of 02 Levobupivacaine with 25 mcg Fentanyl and 02 Ropivacaine with 25 mcg Fentanyl given epidurally for postoperative analgesia in patients w...
Attenuation of cardiovascular response to laryngoscopy and tracheal intubation by a bolus dose of inj. esmolol and placebo – A comparative study
Introduction and Objectives: Laryngoscopy and tracheal intubation are noxious stimuli that produce marked sympathetic responses manifesting as tachycardia and hypertension, which can be deleterious in susceptible-patient...