Role of Neutrophilic Lymphocytic Ratio in prognosis of patients with stroke

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Role of Neutrophilic Lymphocytic Ratio in prognosis of patients with stroke

Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 1

Abstract

Abstract: The present study was undertaken at Dr. S. N. medical college which included 96 (Male/female: 59/37) patients presenting with acute stroke. Majority of the patients were from age group 40-75 year of age (72.92). Of the total 73 patients had AIS and 23 had AHS. The AHS patients had significantly higher mortality rate (p<0.05). Patients who expired were of significantly higher age group as compare to survived patients (p<0.05). Of the total 31 expired patients in our study, 16 (51.6%) expired during the hospital stay and rest 15 (48.4) patients expired within 3 months of event after discharge. On admission mean NLR was found significantly higher in patients those died as compare to survived patient, (8.96±7.98; 6.04±5.03;p<0.05). The NLR value of >4.814 had significantly higher mortality rate (p<0.001). The cut off value of NLR >4.814 demonstrated a sensitivity of 67.74%, specificity of 58.46%, positive Predictive Value of 43.80%, negative Predictive Value of 79.20% and AUC was 0.634. ROC curves were constructed to assess the predictive value of NLR. The mortality rate was statistically significantly higher for cut off value of ANC >6570 (p<0.002). The cut off value of ANC >6570 for mortality rate of acute stoke had sensitivity of 80.65%, specificity of 47.69%, Positive Predictive Value of 42.4%, negative Predictive Value of 83.8% and AUC = 0.616. In conclusion, NLR is a readily available and inexpensive biomarker for predicting the short term mortality for acute CVA. It can be utilized as a robust stand-alone prognostic marker for patients presenting with stroke. Keywords: stroke, prognostic marker, AHS, CVA

Authors and Affiliations

Ram Babu Gurjar, Dhan Raj Bagri, Hansraj Pahadiya

Keywords

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EP ID EP370570
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