ROLE OF PROPOLIS IN AUGMENTING THE BUCCAL MUCOADHESION- AN EXPERIMENT BASED REPORT
Journal Title: Hygeia:journal for drugs and medicines - Year 2015, Vol 7, Issue 1
Abstract
Plan: The present research has been undertaken with the aim to develop an oral mucoadhessive gel for gingivitis and periodontitis, evaluation of its physicochemical characteristics. Preface: Gingivitis and periodontitis require prolonged medication which is challenging with the nature and anatomy of the oral cavity. Here a sincere attempt was done to enhance the adhesion and contact time of a developed oral adhesive medicament by virtue of its protective layer itself should prevent abrasions, thus aiding in healing. Methodology: In the contemporary work, effect of propolis, vitamin C and vitamin E on mucoadhessive nature of oral adhesive dosage form intended for the treatment of gingivitis were investigated. Oral mucoadhessive preparation was prepared by preparation of emulsion system and incorporation into gel to form an emulgel. This emulgel was compared for its physiochemical characterization with gel in the presence and absence of propolis extract. The work was further enhanced by considering a combination of vitamin C and E incorporated gel. Outcome: From the study it was concluded that excellent mucoadhesion resulted by addition of propolis, vitamin C, vitamin E. Results clearly indicated propolis because of mucoadhesion can augment the contact time of the medicament with that of the oral cavity. Freeze thaw cycles of stability Performa indicated the propolis-emulgel combination was stable for 8 cycles and there was no globule size alteration, means no agglomeration tendency.
Authors and Affiliations
Vinod KR, Fidoski Jasmin, Jun- Woo Park, Ferda Alev Akalin, Dong- Ju Choi
Keywords
Related Articles
- EP ID EP401488
- DOI 10.15254/H.J.D.Med.7.2015.140
- Views 73
- Downloads 0
A REVIEW ON NOVEL ORAL ANTICOAGULANTS
Plan: This article reveals the significance of novel oral anticoagulants in place of conventional vitamin K antagonists. Vitamin K antagonists were commonly used since 1941 but it has lot of inconveniences. Preface: An...
TRADITIONAL AYURVEDIC TABLETS MAY CONTAIN HEAVY METALS
Plan: Several authors have reported the presence of alarmingly high levels of heavy metals like lead, arsenic, cadmium and mercury in ayurvedic medicines. Ayurveda employs several classes of medicines, among which gulik...
HERBAL BIOACTIVES AND FOOD FORTIFICATION
he lifestyles of people worldwide have changed in the last century due to a rise in income, increased leisure time, and reduced physical activity. These new lifestyles have a considerable impact on health. Consequently,...
Synthesis and Characterization of some New 2-Methyl-3-N-Substituted Imino - 5, 6-Tetramethylene Thieno [2, 3-D]-Pyrimidin (3h)–4-ones for Anti-bacterial and Antifungal screening
Plan: To synthesize some Schiff bases of 2-Methyl-3-N-amino-5, 6-disubtituted thieno [2, 3-d] - pyrimidin (3H)-4-ones for antibacterial and antifungal activities. Preface: Organic compounds containing thiophene and pyrim...
HEAVY METALS IN AYURVEDIC MEDICINES
Ayurveda is the traditional medicine of India that has been practiced since ancient times. According to the modest estimates made by European scholars, it has a track record of 20 centuries. However, protagonists of the...