Scrotal neoplasms: A histopathological study
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 5
Abstract
Background: Testicular tumours are a heterogenous group of neoplasms with variable histopathology, clinical course and prognosis. A wide range of histologic types of testicular tumours are recognized, the majority of which originate from the germ cell. Tumours of the paratesticular tissue are encountered only rarely. Methodology: Retrospective study of eleven cases selected from the archives of the Pathology Department. Detailed clinical and laboratory information was recorded from the patient's files. The sections were prepared from formalin fixed paraffin-embedded tissues and stained with Haematoxylin and Eosin. Results: Out of the twelve cases studied, there were five cases of seminoma, two cases of mixed germ cell tumour and one case of Non Hodgkins Lymphoma of the testis. The cases of seminoma were in the age group of 25-65 years. Elevated levels of serum LDH were noted in allthese cases. In the case of the mixed germ cell tumour alpha-fetoprotein and human Chorionic Gonadotrophin were found to be elevated. There were three cases of papillary cystadenoma and one adenomatoid tumour of epididymis. Conclusion: Germ cell tumours form the largest majority of the testicular tumours. Seminoma accounts for 50% of these. It is also the most likely germ cell tumour to present with a single histologic pattern. Mixed germ cell tumours are rare. Testicular lymphomas constitute 2% of all testicular neoplasms. Adenomatoid tumours are the most common tumours of the testicular adnexa.
Authors and Affiliations
Shikha Jayasheelan, Prema Saldanha
Keywords
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