SENSITIVITY STATUS OF MYCOBACTERUM TUBERCULOSIS COMPLEX STRAINS ISOLATED IN OUR CLINIC TO ANTITUBERCULOSIS DRUGS
Journal Title: Kocatepe Medical Journal - Year 2021, Vol 6, Issue 22
Abstract
OBJECTIVE: Tuberculosis (TB) is a chronic infectious disease caused by microorganisms belonging to the Mycobacterium tuberculosis complex (MTBK) group. This disease is treated and controlled with antituberculosis drugs; but sometimes it may not respond to medications. Investigation of drug resistance in tuberculosis, forms the basis of tuberculosis control and treatment programs. MATERIAL AND METHODS: In our study, it was aimed to investigate the susceptibility of MTBK isolate, isolated in our laboratory to primary antituberculosis drugs and to determine their resistance patterns. Between 2011 and 2019, 8804 clinical samples sent to the microbiology laboratory with the suspicion of tuberculosis were evaluated in our clinic. RESULTS: Tuberculosis culture was positive in 126 of the samples included in the study. Anti-tuberculosis susceptibility test was applied to 126 samples (1.4%). 28 (22.3%) isolates were found to be resistant to at least one of the tested antituberculosis drugs tested. Multidrug resistance was found at the rate of 2.38%. CONCLUSIONS: In order to prevent the development of resistance in the treatment of tuberculosis and to provide a healthy treatment, culture and antibiotic sensitivity tests should be performed for each patient and data should be obtained.
Authors and Affiliations
Aydın BALCI, Ersin GÜNAY,Cengiz DEMİR, Şule ÇİLEKAR, İbrahim Güven COŞĞUN, Suphi AYDIN
Keywords
Related Articles
- EP ID EP697204
- DOI https://doi.org/10.18229/kocatepetip.802182
- Views 98
- Downloads 0
DEFENSIVE MEDICINE APPROACH IN PATIENT ASSESSMENT BY EMERGENCY DEPARTMENT PHYSICIANS
OBJECTIVE: The most distinctive feature of defensive medicine is that the physician wants to protect herself against the risk of being sued by the patient and her relatives by performing medical procedures that are not n...
THE IMPORTANCE OF GENOME COPY NUMBER VARIATIONS IN CHILDREN WITH A DIAGNOSIS OF HYPOTONIA
OBJECTIVE: Hypotonia is a general term used to denote reduced tone in the limbs, trunk, or craniofacial skeletal muscles. Itcan be detected at birth or later in childhood. It is importantto establish the diagnosis, predi...
INVESTIGATION OF THE RELATIONSHIP OF COMPUTED TOMOGRAPHY HISTOGRAM ANALYSIS WITH SURVIVAL TIME AND LOCAL CONTROL TIME IN HEAD AND NECK SQUAMOUS CELL CARCINOMA TREATED WITH CHEMORADIOTHERAPY
OBJECTIVE: This study aimed to evaluate the association between computed tomography (CT) histogram analysis and overall survival and local control in head and neck squamous cell carcinoma (HNSCC) treated with chemoradiot...
DETERMINATION OF NURSING STUDENTS' ATTITUDES TOWARDS STIGMATIZATION BY OTHERS FOR SEEKING PSYCHOLOGICAL HELP FOR THEIR MENTAL SYMPTOMS
OBJECTIVE: To determine the mental symptoms of nursing students and their attitudes towards stigmatization by their close circle when seeking psychological help. MATERIAL AND METHODS: The population of the research, whi...
WAS IMMUNOGLOBULINS EFFECTIVE IN DISEASE SEVERITY AND LENGTH OF HOSPITAL STAY IN CHILDREN WITH THE INFECTION OF SARS-COV-2 ?
OBJECTIVE: We investigated whether immunoglobulin levels on admission are associated with disease severity, time to negativization of SARS-CoV-2 RT-PCR test, and length of hospital stay in children with severe illness re...