Seroprevalence and seasonal trend of dengue virus infection at tertiary care hospital, Valsad
Journal Title: Medpulse International Journal of Microbiology - Year 2019, Vol 9, Issue 3
Abstract
Background: Dengue is a vector borne febrile illness affecting tropical and subtropical regions of world including India. It is major public health problem in India because of rapid explosive urbanisation and absence of specific antiviral treatment. It presents with mild fever and ends with life threatening complication like Dengue Shock Syndrome or Dengue Hemorrhagic Fever. Regular epidemiological surveillance and appropriate vector control measures is the only way to prevent transmission of diseases. Aims and Objective: To study the prevalence of Dengue virus infection with seasonal trend at tertiary care hospital, Valsad. Materials and Methods: The study was conducted from July 2015 to December 2018 at tertiary care hospital, Valsad. Blood samples from suspected cases were collected and tested for NS1 antigen detection by Dengue NS1 Ag enzyme immunoassay kit and for IgM antibody by NIV Dengue IgM capture ELISA kit based on their duration of illness. Result: Out of total 2830 serum samples tested, 674 (23.81%) were found positive for dengue virus infection. 461 samples were positive from male patients and 213 samples were positive from female patients with male female ration of 2.1:1.The most commonly affected age group was below 20 years of age (25.84%) followed by 21-40 years of age group (24.54%). There is a gradual raise in the positivity rates from July reaching a pick by October. Conclusion: The study concludes that Dengue infection has been established in semi urban area of Valsad with male predominance. Dengue virus infection is high during monsoon and post monsoon seasons due to increase vector breeding. Continuous epidemiological surveillance, appropriate vector control measures and early diagnosis by ELISA are necessary for effective Dengue control programme.
Authors and Affiliations
Mehul Patel, Vicky Gandhi, Hiral Patel, Alka Nerurkar
Keywords
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- EP ID EP486270
- DOI 10.26611/1008931
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