Seroprevalence of hepatitis E virus among blood donors in tertiary care center of north Gujarat
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 3
Abstract
Introduction HepatitisE virus HEV is a RNA virus having single strand and spread mainly through contaminated water and food as well as through parenteral route Very few study has been carried out in India in general public as well as voluntary blood donor to determine HEV prevalence The prevalence of antiHEV in India is limited and the results differ depending on the type of population location and serological test used in the studiesMaterials and Methods Samples from 1345 voluntary blood donations were tested in the period between November 2014 to December 2017 Samples were tested for the presence of antibody against HEVResults The study population which composed of 1280 male 65 Female voluntary blood donors Age of study group ranged from 18 to 60 years with a mean age of 3248 years Overall the harmony among the three ELISA was 926 corresponding to a prevalence rate of 275 371345 The lowest antiHEV antibody prevalence values were seen in the younger age groups while the highest prevalence rates were found in the higher age group No significant variation in antiHEV antibody prevalence was noticed between gendersConclusion Although hepatitis E is transmitted by fecoral route seroprevalence of antiHEV antibody among blood donors need to be addressed using available ELISA test or Polymerase chain reaction Blood banks in India and other developing country should consider screening for HEV especially when blood transfusion is given to patients with low immunity or women having pregnanacyKeywords Hepatitis E Blood donor Seroprevalence
Authors and Affiliations
Nimisha Shethwala, Amar Shah, Venu Shah
Keywords
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- EP ID EP475925
- DOI 10.18231/2394-6792.2018.0086
- Views 46
- Downloads 0
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