Serum lactate as a predictor of outcome of sepsis – study
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2017, Vol 4, Issue 4
Abstract
Introduction: Serum Lactate is known to be elevated in subjects with sepsis. Increased blood lactate levels are common in critically ill patients. Some studies revealed its association with prediction of morbidity and mortality. Hence this study was taken up to assess the levels of serum lactate in sepsis and its outcome. Materials and Method: This study comprised of age and sex matched groups consisting of 100 healthy individuals and 100 patients with septicemia who were admitted in MICU. Blood samples were collected and serum lactate levels were analyzed. Results: It was observed that serum lactate altered significantly (P< 0.0001) in subjects with sepsis when compared with healthy control group. The serum lactate levels were raised significantly high in cases with sepsis with outcome as death (P< 0.0001) in comparison to the subjects who had recovery. Conclusion: Hence serial lactate measurements would be useful as a very good predictor of morbidity and mortality during the course of sepsis in elderly individuals.
Authors and Affiliations
G. Lakshmi Chaitanya, D. Sridevi, Amrut A. Dambal, Sidrah . , Girija Menon
Six sigma in clinical biochemistry: It matters, measure it
Introduction: Accurate test results are the core of healthcare system since physician's decisions mostly depends on the laboratory results. The evaluation of laboratory performance is critical to maintain accurate labora...
Application of failure mode and effects analysis to minimize quality failures in clinical biochemistry laboratory
Introduction Quality failures in the clinical laboratories should be analyzed to improve patient safety in hospital Purpose of this study is to apply failure mode and effects analysis FMEA for prospective risks of qualit...
Correlation of HbA1c with atherogenic index of plasma and endothelial dysfunction in type 2 diabetic subjects
Introduction Endothelial dysfunction ED is a well known initial stage of atherosclerosis and cardiovascular disease CVD in general population Recently studies shown increased HbA1c is a marker for cardiovascular risk in...
Total antioxidant status and serum lipid profile in hypothyroid patients in tertiary care hospital of Northern India
Objective: To study the Total Antioxidant status, thyroid profile and lipid profile in patients of overt and subclinical hypothyroidism. Also to assess the sex differences in thyroid function and to compare our results t...
Prevalence of overt and subclinical thyroid disease in patients tested for thyroid profile in CIMS Bilaspur (C.G.)
Background: Thyroid diseases are common worldwide. In India too, there is a significant burden of thyroid diseases. According to a projection from various studies on thyroid disease, it has been estimated that about 42 m...