Significance of Molecular Genotyping for Lung Cancer in Modern Oncology
Journal Title: Pulmonary Research and Respiratory Medicine – Open Journal - Year 2015, Vol 2, Issue 3
Abstract
Lung cancer is one of the most prevalent life-threatening diseases and remains the leading cause of cancer-related death worldwide. Although surgical resection of the tumor is considered as one of the most effective treatments, most lung cancer patients present with locally advanced or metastatic disease at the time of the diagnosis and are not candidates for surgical treatment. For these patients palliative chemotherapy and radiation therapy, alone or in combination, become the main treatment of choice. The prognosis for lung cancer in general is poor and an overall 5-year survival rate for all stages of lung cancer, regardless of subtypes, is about 18%, which has not been significantly improved in the past several decades. For those in an advanced stage of the disease the prognosis is even worse. About half of all lung cancer patients have metastatic disease at the time of diagnosis with a 5-year survival rate of less than 5%. There is no doubt that the conventional treatment of lung cancer would not significantly change the outcome for lung cancer patients.
Authors and Affiliations
Zhaolin Xu
Keywords
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- EP ID EP550123
- DOI 10.17140/PRRMOJ-2-119
- Views 124
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