SIMULTANEOUS DETERMINATION OF CURCUMIN AND GEFITINIB IN PURE FORM BY USING UV SPECTROPHOTOMETRIC METHOD
Journal Title: Hygeia:journal for drugs and medicines - Year 2017, Vol 9, Issue 1
Abstract
Plan: Development and Validation of a method for the UV simultaneous determination of curcumin and Gefitinib. Preface: U.V Spectrophotometric method have been widely employed in determination of individual components in a mixture or fixed dose combination. For the ternary mixture containing Curcumin and Gefitinib, no spectrophotometric method for simultaneous evaluation has been reported so far. Thus our aim is to develop simultaneous equation method for estimation of the ternary mixture using U.V spectrophotometry. Methodology: The method was validated as per ICH guidelines. The recovery studies confirmed the accuracy and precision of the method. Outcome: It was successfully applied for the analysis of the drug in bulk and could be effectively used for the routine analysis.
Authors and Affiliations
SAGAR Savale
NEWER ANTIPLATELET AGENTS IN CARDIOVASCULAR DISEASE
Plan: Antiplatelet drugs are the corner stone in the treatment of cardiovascular disease. They remain the main stay in preventing aberrant platelet activation in pathophysiological conditions like myocardial infarction,...
PHARMACOGNOSTICAL STANDARDIZATION OF AERIAL PARTS OF Rosmarinus officinalis Var. Albus
Plan: Rosmarinus officinalis Albus is a woody, perennial herb with fragrant, evergreen, needle-like leaves and white flowers grown in many parts of the world. It is widely used in the treatment of genitourinary condition...
Preliminary phytochemical analysis of methanolic extract of Tinospora cordifolia and its anti-bacterial action on E.coli cell division
Plan: The study involves the antibacterial screening the methanolic extract of Tinospora cordifolia and its preliminary phytochemical analysis. Preface: Bacterial infections have become increasingly difficult to treat b...
ROLE OF PROPOLIS IN AUGMENTING THE BUCCAL MUCOADHESION- AN EXPERIMENT BASED REPORT
Plan: The present research has been undertaken with the aim to develop an oral mucoadhessive gel for gingivitis and periodontitis, evaluation of its physicochemical characteristics. Preface: Gingivitis and periodontitis...
PHYTOCHEMICAL STUDIES OF BIOACTIVE COMPOUNDS FROM Cucumis melo LINN.
Objective: The present study deals with the qualitative identification of phytochemical constituents from Cucumismelo Linn fruits and seeds Method: The methanolic extract of both fruit and seed was subjected to phytoch...