SOLID LIPID NANOPARTICLES: A PROMISING DRUG DELIVERY SYSTEM
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 4
Abstract
Solid lipid nanoparticles are at the forefront of the rapidly developing field of nanotechnology with several potential applications in drug delivery, research and clinical medicine, as well as in other varied sciences. Solid lipid nanoparticles (SLNs) technology represents a promising new approach to lipophilic drug delivery. Nanoparticles are solid colloidal particles ranging in size from 1 to 1000 nm and composed of macromolecular material. The biodegradable and bioacceptable nature of SLNs makes them less toxic as compared to polymeric nanoparticles. SLNs can also be used to improve the bioavalability of drugs. In this present review this new approach is discussed in terms of their advantages, characterization, pharmacokinetic studies, in-vivo studies, in-vitro studies, and special features.
Authors and Affiliations
A. S. Waghmare , N. D. Grampurohit , M. V. Gadhave , D. D. Gaikwad , S. L Jadhav
Keywords
Related Articles
- EP ID EP145608
- DOI -
- Views 102
- Downloads 0
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD IN MULTI-COMPONENT FORMULATION
The aim of the present work was focused on development of an analytical method for simultaneous estimation of drugs in multi-component dosage form by using RP-HPLC. Chromatographic separation techniques are one of the mo...
EVALUATION OF ANTIBACTERIAL ACTIVITY OF HERBS
Medicinal plants have been used for centuries as remedies for human diseases because they contain components of therapeutic value. The acceptance of traditional medicine as an alternative form of health care and the deve...
AUDITORY REACTION TIME IN BASKETBALL PLAYERS AND HEALTHY CONTROLS
Reaction is purposeful voluntary response to different stimuli as visual or auditory stimuli. Auditory reaction time is time required to response to auditory stimuli. Quickness of response is very important in games like...
EVALUATION OF ANTI-OXIDANT AND ANTI-DIABETIC ACTIVITIES OF CINNAMOMUM TAMALA LINN LEAVES IN STREPTOZOTOCIN-INDUCED DIABETIC RATS
The main objective of this study was to focus on the anti-diabetic activity of Cinnamomum tamala Linn, with special reference to its curative and protective role in streptozotocin- induced diabetic animal model. Attempts...
ANTIDEPRESSANT ACTIVITY OF HYDROALCOHOLIC EXTRACT OF ZINGIBER OFFICINALE
The present study was design to evaluate the effect of Zingiber officinale hydro-alcoholic extract as well as its interaction with conventional anxiolytic and antidepressant drugs using tail suspension test and forced sw...