SPECIFIC AND NON-SPECIFIC IMMUNE RESPONSE AND DISEASE RESISTANCE OF SOLANUM TORVUM LEAF SOLUBLE FRACTIONS IN FRESHWATER CARP CYPRINUS CARPIO
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 6
Abstract
The immunostumulatory effect of the leaves extract of a medicinal plant Solanum torvum (Turkey Berry), On Specific, non-specific immune responses and disease resistance of Common carp Cyprinus carpio was investigated. Fish were intraperitoneally injected with 0, .8, 80 or 800 mg kg-1 body weight, of the water soluble fraction. The non-specific humoral (Lysozyme activity) and cellular (Hematology and Agglutination) responses and disease resistance against Aeromonas hydrophila and nutraceutical effect of S. torvum leaf powder supplementation on fish Growth estimation. All the doses of water-soluble fraction tested, significantly enhanced the serum Lysozyme activities and Agglutination and Total Serum Protein on 45 days experimental Period. The highest Lysozyme activity and agglutination was observed in the group fed with 80 mg of S. trovum feed for 45 days the results were Significantly (p<0.05). Hematological parameters of experimental groups were significantly increase compared with control groups. The maximum growth was observed in 80mg S. torvum fed fish and decreased growth was observed in 0.8 mg and 800mg of herbal diet fed fish (P < 0.05) compared with non-supplemented control fish. The results clearly indicate the immunostimulatory and disease resistance properties of S. torvum leaf fraction and so its potential to be used as an first grade immunostimulants in fresh water aquaculture.
Authors and Affiliations
V. Uthayakumar , V. Ramasubramanian , D. Senthilkumar , P. R. Sreedevi, S. Munirasu
Keywords
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