Spectroscopic characterization and Bioactivty studies of new Co(II), Ni(II), Cu(II), Au(III) and Pt(IV) complexes with didentate (NO) donar azo dye ligand
Journal Title: International Journal of Medical Science and Dental Research - Year 2018, Vol 1, Issue 1
Abstract
: The.newligand(5-((4-(1-(p-tolylimino)ethyl)phenyl)diazenyl)pyrimidine -2,4,6(1H, 3H, 5H) -trione (R2) have been synthesized and characterized by micro elemental analysis ,(1H13C) NMR, FT-IR, and UV-Vis spectroscopic techniques. (R2 ) acts as a ligand coordinating with some metal ions Co(II), Ni(II), Cu(II), Au(III) and Pt(IV) generated fife mononuclear metal complexes, represented as [CoR2Cl2(H2O)2] (a) ,[NiR2Cl2] (b),[CuR2Cl2] (c),[Pt(R2)2 Cl2 ] Cl2 (d) , [Au(R2)2]Cl3(e) .The Structures of the new compounds were characterized by elemental , FT-IR and UV-Vis Spectra. The magnetic properties and electrical conductivities of metal complexes were also determined. The anticancer activity for (R2) and its metal complexes complexes have been extensively studied on AMGM cancer cell line.
Authors and Affiliations
Huda Abbas, REHAB AL-HASSANI
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