STABILITY EVALUATION OF TOPICAL OINTMENT COMPRISING CALCIPOTRIOL AND PREDNICARBATE
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2015, Vol 6, Issue 1
Abstract
Stability studies ensuring the maintenance of product quality, safety and efficacy throughout the shelf life are considered as pre-requisite for the acceptance and approval of any pharmaceutical product. The objective of present investigation was to study the stability of a two-compound ointment containing Calcipotriol and Prednicarbate formulated using polyoxypropylene – 15-stearyl ether and Vitamin E Acetate when stored at different conditions for specific duration of time. Stability on storage is an important aspect which ensures the dosage form can exert the effects it is supposed to exert for the duration of storage. Appearance, drug content, pH and microbiological parameters are the parameters that have been assessed under different temperature to evaluate the stability of the ointment. The data obtained from the stability study showed that this formulation is stable for the 6 months period when stored at real time conditions.
Authors and Affiliations
Jyoti Phatangare , Sharada Deore , Kundan Phatangare
Keywords
Related Articles
- EP ID EP100256
- DOI 10.7897/2230-8407.06110
- Views 71
- Downloads 0
INVESTIGATION OF POSSIBLE HYPOGLYCEMIC AND HYPOLIPIDEMIC EFFECT OF METHANOLIC EXTRACT OF SESBANIA GRANDIFLORA
Sesbania grandiflora (Leguminosae: Papilionoideae), cultivate all over India, has wide range of therapeutic actions. The aim of the current study has been to investigate the possible hypoglycemic and hypolipidemic effect...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF METAXALONE IN BULK AND ITS PHARMACEUTICAL FORMULATION BY UV SPECTROSCOPIC METHOD
Metaxalone, a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains and othermusculoskeletal conditions. A simple, accurate, precise, reproducible, highly sensitive, economic UV spectrophotome...
DEVELOPMENTAL CHANGES IN THE GERMINATION, GROWTH AND CHLOROPHYLLASE ACTIVITY OF VIGNA MUNGO L. USING SEAWEED EXTRACT OF ULVA RETICULATA FORSSKAL.
The effect of seaweed extract prepared from Ulva reticulata on seed germination, seedling growth and chlorophyllase activity of Vigna mungo L. was studied. 100% germination was recorded in the seeds treated with lower co...
PHARMACOGNOSTIC AND PHYTOCHEMICAL EVALUATION OF OUGENIA DALBERGIOIDES BARK
Ougenia dalbergioides (Fabaceae), is commonly known as Sandan. It is reported to have good medicinal values in traditional system of medicine. According to Ayurveda the bark is used in dysentery, leucoderma, urinary dis...
IN VITRO ANTIMICROBIAL ACTIVITY OF LEAVES AND BARK EXTRACTS OF FICUS RELIGIOSA (Linn.)
In the present study we investigated antimicrobial activity of diethyl ether and methanol extractions of bark and leaves of Ficus religiosa plant against three bacteria (E.coli, Staphylococcus aureus & Pseudomonas a...