Structural Elucidation of Cobalt (II) Complexes of 2-Imino-3-(2-hydroxyphenyl)-1-oxozolodin-4-one and Study of its Antimicrobial Relevance
Journal Title: UNKNOWN - Year 2019, Vol 9, Issue 2
Abstract
Complex of Co(II) with heterocyclic ligand [2-imino-3-(2-hydroxyphenyl)-1-oxazolodin-4-one] has been synthesized and characterized with the help of elemental analysis, magnetic, 1H-NMR, 13C-NMR, IR and electronic spectral data. IR spectra exhibit the coordination of the ligands to the metal ion through deprotonated phenolic oxygen and heterocyclic nitrogen. All these studies reveal square planar geometry of Co (II) complexes. Synthesized compounds have also been screened against some micro-organisms viz. Escherichia coli, S. aureus, Aspergillus niger and R. bataticola by ‘paper disc’ techn ique. It has been observed that the antimicrobial activities of metal complexes are higher than that of the free ligand
Authors and Affiliations
Desalegn Demise Sage, Ermias Tamiru, Upadhyay RK
Isolation and Characterization of Compounds from the Leaves of Melia azedarach and Stem Bark of Albizia schimperiana and Evaluation for Antimicrobial Activities
Infectious diseases remain a major threat to public health. Despite tremendous progress in human medicine, their impact is particularly great in developing countries because of the relative unavailability of...
Synthesis and Characterization of New Coumarin Substituted Chromone (8-Methyl-4-phenyl-2H,10H-pyrano[2,3-f] chromene-2,10-dione) Using Benzyl Acetoacetate and Studied their Fluorescence Properties
In the present review developed a new method for synthesis coumarin substituted chromone, as they are an important building block in organic chemistry. Also, they are valuable synthetic intermediates in the preparation o...
Synthesis of Multi-Target Benzene-Sulphonamide Derivatives for the Treatment of Trypanosomiasis
Some derivatives of benzene-sulphonamides were synthesized via condensation reaction. Pharmacokinetic parameters were evaluated to assess the oral bioavailability, permeability and transport properties of the compounds....
Potential Anticancer Agents: Design, Synthesis of New Pyrido[1,2-a]benzimidazoles and Related Derivatives Linked to Alkylating Fragments
The incentive of the present work has been primarily directed towards the design and synthesis of some novel pyrido[1,2-a]benzimidazoles with specific functionalities believed to have alkylation ability. This combination...
Antimicrobial, α-Glucosidase and Alkaline Phosphatase Inhibitory Activities of Bergenin, The Major Constituent of Cissus populnea Roots
Bergenin (1) was isolated as the major compound of the Roots of Cissus populnea. Its structure was elucidated on the basis of spectral analysis, including 1D and 2D NMR experiments and Mass Spectrometry (MS) as well as b...