Struma Ovarii with Pseudo-Meigs’ Syndrome and Raised Cancer Antigen-125 Levels Masquerading as an Ovarian Carcinoma Case report and literature review
Journal Title: Sultan Qaboos University Medical Journal - Year 2017, Vol 17, Issue 2
Abstract
Te monodermal teratoma struma ovarii is a rare ovarian tumour; however, struma ovarii presenting with pseudo-Meigs’ syndrome and raised cancer antigen (CA)-125 levels is even rarer. In elderly patients, this presentation can potentially lead to a misdiagnosis of a malignant ovarian carcinoma, resulting in unnecessary extensive surgery. We report a 55-year-old female who presented to the Lok Nayak Jai Prakash Narayan Hospital, New Delhi, India, in 2016 with progressive abdominal discomfort, fatigue and abdominal distention. Clinical and radiological features were indicative of a malignant ovarian tumour and ascites. Serum CA-125 levels were elevated at 258 U/mL. A left-sided salpingo-oophorectomy was performed, after which the serum CA-125 levels normalised. Tere was no evidence of recurrence at a six-month follow-up. A frozen section procedure confrmed the diagnosis of a struma ovarii. Tis rare condition should be considered as a differential diagnosis in patients presenting with ovarian masses, ascites and raised CA-125 levels.
Authors and Affiliations
Surekha Yadav| Department of Pathology, Maulana Azad Medical College, New Delhi, India, Reena Tomar| Department of Pathology, Maulana Azad Medical College, New Delhi, India, Nidhi Verma| Department of Pathology, Maulana Azad Medical College, New Delhi, India, Nita Khurana| Department of Pathology, Maulana Azad Medical College, New Delhi, India, Rewa Triathi| Department of Obstetrics & Gynecology, Lok Nayak Jai Prakash Narayan Hospital, New Delhi, Delhi, India
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