STUDY OF ANTIOXIDANT ACTIVITY WITH REDUCTION OF DPPH RADICAL AND XANTHINE OXIDASE INHIBITOR OF THE EXTRACT OF RUELLIA TUBEROSA LINN LEAF
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 11
Abstract
Ruellia tuberosa L belongs to Acanthaceae family. In traditional medicine has been used as diuretic, antidiabetic, antipyretic and antihypertensive, and it also recently been incorporated as a component in a herbal tea in Taiwan. This research aims to determine the antioxidant activity of R. tuberosa leaf extract. Extraction of R. tuberosa leaf by stratified maceration method using dichloromethana and methanol. Methanol extract was partitioned by using ethyl acetate and n-butanol. Antioxidant activity was tested by reduction of DPPH radical method and inhibition of the xanthine oxidase. The results show n-butanol extract has an antioxidant activity with reduction of DPPH radical and inhibition of the enzyme xanthine oxidase with IC50 value respectively 7.42 and 0.15 µg/mL.
Authors and Affiliations
Roskiana Aktsar , Munim Abdul , Elya Berna
Keywords
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