Study of Efficacy of Cilostazole in Peripheral Arterial Occlusive Disease
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 2
Abstract
Peripheral arterial occlusive disease (PAOD), commonly referred to as peripheral arterial disease (PAD) or peripheral vascular disease (PVD), refers to the obstruction or deterioration of blood flow through the arteries, exclusive of the coronary and intracranial vessels.1 The incidence of symptomatic PAD increases with age, from approximately 0.3%/ year for men aged 40 to 55 years to approximately 1%/year for men older than 75 years.2 Peripheral arterial occlusive disease is an important manifestation of atherosclerosis involving the arteries of legs.3 Vascular surgeons continue to encounter complications of atherosclerosis as their most common clinical challenge.4 This observational study was conducted with patient receiving 100mg Cilostazole twice daily and assessing the claudication distance at the end of 3months. There was statistically significant increase in the claudication distance in patients receiving Cilostazole. We concluded Cilostazol is an effective drug in increasing claudication distance in patients with peripheral vascular occlusive disease.
Authors and Affiliations
Sattar Khan, Divakar Shenoy
Keywords
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