Study of glycated haemoglobin and serum adenosine deaminase in patients with type II diabetes mellitus with and without diabetic nephropathy or retinopathy
Journal Title: Medpulse International Journal of Medicine - Year 2019, Vol 9, Issue 3
Abstract
Background: Diabetes Mellitus refers to a group of common metabolic disorders that share phenotype hyperglycemia. Several distinct types of DM are caused by complex interaction of genetic and environmental factors such as lifestyle, alcohol, diet, smoking, obesity etc. Aims and objective: To study and compare concentrations of HbA1c and sr. ADA in DM type 2 with and without DM retinopathy or nephropathy, and Dm without microangiopathy. Materials and methods: The present study was a hospital based cross sectional observational study. Prior to study approval of IEC of BVDU medical college sangli. Data of type 2 DM indoor patients, was collected over a period of 1 year from 1st march 2015 to 29th Feb. 2016. All patients blood samples from selected patients fasting Blood sugar (FandPP), Hba1C,sr, ADA send to Bharati Hospital Biochemistry lab. HbA1c was measured using Nephlometery and sr. ADA was estimated using Hypoxanthine Method and urine microalbumin test was done using dip test, fundoscopy was done by Senior ophthalmologists, statistics using mean and standard deviations t and chi-square test. Observations, results and conclusion: Results of the present study suggest of a positive correlation of Sr. ADA with microvascular complications in DM retionopathy and nephropathy. Raised levels of sr. ADA can be considered as chronic microvascular complications. And HbA1c is better more reliable and specific.
Authors and Affiliations
Vasant Baburao Jadhav, Anurag Shirish Chavan
Keywords
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- EP ID EP516645
- DOI 10.26611/1021931
- Views 41
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