Study of rabies and development of preparations and methods of its prevention in the Republic of Belarus
Journal Title: Бюлетень "Ветеринарна біотехнологія" - Year 2018, Vol 33, Issue
Abstract
Introduction. Rabies is an absolutely deadly acute viral disease that affects a person and all warm-blooded animals, which is common in many countries of the world, including in Belarus. Due to its socio-economic importance, it occupies one of the leading places in infectious pathology, and therefore, an extremely important attention is given to its study, development of prevention and control measures. The goal of the work. Conduct an analysis of existing and determine the prospects for future developments in the field of means and methods of preventing rabies of wild carnivores. Results of research and discussion. The results of studying of rabies in Belarus on the basis of the State Institution “RSPC of Epidemiology and Microbiology” and RUE “Institute of Experimental Veterinary named of S.N. Vyshelessky”. The data of researches in the field of epizootology and epidemiology of rabies in the Republic, pathogenesis and improvement of diagnostics are presented. Particular attention was paid to the development of rabies vaccines and the method of oral vaccination of wild carnivores against rabies. Conclusions and prospects for further research. As a result of conducted researches by the employees of “Institute of Experimental Veterinary named of S.N. Vyshelessky” a liquid culture inactivated rabies vaccine “BELRAB”, the vaccine “Rabirif” for post-exposure prophylaxis of rabies, polyvalent vaccines against rabies, parvovirus enteritis, distemper and infectious hepatitis of carnivores were developed. A highly biologically active vaccine rabies virus (KMIEV-94 strain) was selected, the technologies of its suspension cultivation in BHK-21/13 cell culture and producing of oral vaccine blister packs were developed.
Authors and Affiliations
Yuriy Lomaka, Nikolai Kovalev, D. V. Buchukuri, Dmitry Borisovets, T. A. Zuykevich
Keywords
Related Articles
- EP ID EP410094
- DOI 10.31073/vet_biotech33-10
- Views 101
- Downloads 0
Influence of aminoacids on Bacillus genus bacteria spore germination
The study applies experimental approaches to spore germination to determine whether the germinants will affect the two different species B. cereus and B. anthracis using in vitro tests. Carrying out studies on the vacc...
The problem of Pseudomonas aeruginosa antibiotic-resistance and search of effective means of fighting
Introduction. Pseudomonas aeruginosa (P. aeruginosa) is one of the “traditional” pathogens of purulent-septic diseases and complications, which causes about 30–70% of nosocomial infection cases. The causative agent has m...
Obtaininig of primary cell culture from freshwater molluscs
Introduction. Molluscs have the ability to regenerate, but they are not characteristic of malignant tumors. All attempts to get inoculated cell line cultures from the tissue of these animals were not successful. Perhaps...
Influence of cryopreservation on the genetic stability of the cat stem cells in dependence on their source
Introduction. An important issue of the cell therapy is the long-term preservation of the cell material. Currently, cryopreservation is used for this purpose. In the process of the cell material freezing, there are two m...
The influence of knemidocoptosis causes on the general state of decorative birds
Introduction. Knemidocopes spend most of their lives in the epidermal layer of the skin of pet birds. Sliding, ticks with their bristles and suckers on their tarsal segments, irritate the skin receptors and cause itching...