Study of uric acid in metabolic syndrome and it's correlation with individual components of metabolic syndrome
Journal Title: Medpulse International Journal of Biochemistry - Year 2018, Vol 7, Issue 2
Abstract
Aim: This study was designed to determine levels of serum uric acid (SUA) in patients of metabolic syndrome (MetS) and its correlation with individual components of MetS. Material and Methods: This was cross sectional study which included 75 cases of MetS and 50 controls. 75 cases were further divided in to 3 groups depending up on the number of components of MetS. Anthropometric parameters like height, weight, BMI (body mass index), Waist circumference (WC) were measured. Fasting blood sugar (FBS), serum total cholesterol (TC), serum triglycerides (TG), serum HDL (high density lipoprotein), LDL (low density lipoprotein), VLDL (very low density lipoprotein), systolic and diastolic blood pressure (SBP, DBP) and SUA were measured in each individual. And their correlations with each other were studied. Results: SUA was significantly increased in MetS patients than in controls. Level of serum SUA was increased with increase in components of MetS. SUA was positively correlated with WC, TG, SBP and DBP and negatively correlated with HDL. SUA was not correlated with FBS. Conclusion: SUA is significantly increased in MetS patients and it is significantly correlated with WC, TG, HDL, SBP and DBP.
Authors and Affiliations
P S Kadam, J S Bavikar, R J Shendye Roy
Keywords
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