Study on Green Synthesis, Characterization and Anticancer Activity of Thorium Nanoparticles Using Tomato (Lycopersicon Esculentum) Extract
Journal Title: IOSR Journal of Applied Chemistry (IOSR-JAC) - Year 2018, Vol 11, Issue 7
Abstract
In the present study, we experiment the reducing and capping activity of aqueous extract from tomato juice for the preparation of thorium nanoparticles. Structural and morphological studies of these nanoparticles were carried out by using UV-Vis spectroscopy, Transmission Electron Microscopy, Fourier infrared spectroscopy, X-ray Diffraction Analysis and anticancer activities. The average particle size of thorium nanoparticles was found in the range of 1.05nm to 1.67 nm. The use of tomato extract proves the process a nontoxic, cost-free and environmentally friendly green method of production of thorium nanoparticles. Introduction: The subject nanotechnology deals with manufacturing, study and manipulation of matter at nanoscale in size range of 1-100 nm which may be called as nanoparticles [1]. Nanotechnology represents the design, production and application of materials at atomic, molecular and macromolecular scales in order to produce new nanosized materials [2].Nanotechnology is mainly concerned with synthesis of nanoparticles of variable sizes, shapes, chemical compositions and controlled disparity with their potential use for human benefits [3].Their unique properties contribute to their potential applications in various fields like biosensors, bioremediation of radioactive wastes, functional electrical coatings, synthesis of enzyme electrode and particularly in medicine such as delivery of drugs, antigen for vaccination and gene delivery for treatment or prevention of genetic disorder [4,5,6]. This has inspired the scientists to develop effective procedures for the synthesis of nanoparticles. In recent years, metal nanoparticles have received significant attention owing to their unique properties and practical applications [7]. The traditional chemical methods used to synthesize nanoparticles are expensive and often raise questions of environmental risk due to use of toxic, hazardous chemicals. Further, these synthetic methods normally use organic solvents because of hydrophobicity of the capping agents used [8]. Hence, the search for cleaner, nontoxic methods of synthesis has ushered in developing approaches that use biological systems [9.10].It is known that fruit mediated synthesis of thorium nanoparticles is much safer and environmentally friendly as compared to chemical synthesis. Here we report synthesis of thorium nanoparticles by using onion (Lycopersicon esculentum) extract. Through elaborate screening process involving number of fruits, we observed that tomato was potential fruit for the synthesis of thorium nanoparticles. The synthesized nanoparticles were characterized by, Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Fourier infrared (FTIR) spectroscopy, X-Ray Diffraction and anticancer activity.
Authors and Affiliations
U. S Pujeri, A. S. Pujar, M. S. Yadawe
Keywords
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- EP ID EP414351
- DOI 10.9790/5736-1107032529.
- Views 148
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