Study on Relationship Between Hyperuricemia and Dyslipidemia
Journal Title: Journal of Indus Medical College - Year 2019, Vol 2, Issue 1
Abstract
OBJECTIVE: To evaluate the correlation between high serum uric acid levels and lipid profile so as to yield dynamic precautionary actions from emerging imminent cardiovascular ailments. METHODOLOGY: This research study was piloted on 180 adult patients (n=180), 90 hyperuricemic and 90 healthy controls in the Department of Medicine and Physiology, Indus Medical College Tando Muhammad Khan, and the duration of study was six months (from April 2018 to July 2018). Patients who were alcoholic, having diagnosis of chronic hepatic Illness, renal conditions, cardiovascular diseases as well as those taking lipid lowering agents and on the treatments that can disturb uric acid were disqualified from this research study. Lipid profile performed for those who found with raised uric acid levels but without symptoms and those presented with gout. Data catered and evaluated on SPSS version 16.0. Quantitative factors were uttered as mean + standard deviation. To compare the means, student t test was applied. Positive and negative correlation was likewise calculated through regression analysis. RESULTS: This research study revealed significant results with positive association (p < 0.05) between uric acid and total cholesterol, triglycerides and low density lipoprotein. Instead, remarkable negative association observed between uric acid and high density lipoprotein levels (p value < 0.05). CONCLUSION: Hyperuricemia is linked with dyslipidemia that may lead to imminent cardiovascular conditions. Consequently, cardiovascular emergencies can be possibly prevented by diagnosing as well as timely managing in elevated uric acid level and dyslipidemia.
Authors and Affiliations
Ramesh Kumar Suthar, Kavita Bai, Mumtaz Ali Memon, Keenjhar Rani
Keywords
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