Susceptibility Pattern of Escherichia coli to Fluoroquinolones as a Uropathogen: Study in a tertiary care hospital @ Mangadu between 2016 to 2018
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Urinary tract infection (UTI) second largest infection, causing antibiotic resistance strains among uropathogens, urging attention and concern in medical treatment. The common uropathogen reported is Escheriacoli (E.coli), often treated by fluroquinolones. Aim : To update our knowledge on common local uropathogens, study aimed at identifying the common uropathogen in uncomplicated UTI infection and evaluating the susceptibility pattern of Escherichia coli towards the frequently prescribed fluroquinolones for uncomplicated UTI in our tertiary care hospital at Mangadu South India, from August 2016 to August 2018. Study Subjects & Results: A total of 4217 urine samples analysed, common uropathogen was E.Coli (59.6%) from uncomplicated UTI patients. Antimicrobial susceptibility performed for E.Coli towards the five common fluroquinolones showed the pattern of susceptibility as 86.8% Levofloxacin, 73.5% Gatifloxacin, 82.9% Ofloxacin, 47.6% Norfloxacin, and 28.1%, Ciprofloxacin. Resistance was noticed higher towards Ciprofloxacin, Norfloxacin and Ofloxacin. Conclusion: Study was able to standardize the fluroquinolone pattern of antibiotic treatment within the uncomplicated UTI patient group, after the analysis of antibiogram sensitivity in our local population.
Authors and Affiliations
Dhevahi Elumalei, Abhishek A. T. Janaranjani B. Y, Arvind Srinivasan, Keerthana Vijayarajan, Saranya Anbalagan, Anitha . M, Sumathi G.
Keywords
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- EP ID EP415532
- DOI 10.9790/0853-1711065457.
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