Synthesis, Characterization and Biological Screening of Oxadiazole Incorporated Acetamide Derivatives as Potent Antibacterial Agents
Journal Title: Journal of Biological and chemical Chronicles - Year 2018, Vol 4, Issue 1
Abstract
A series of ten derivatives of 2-[(5-aryl-1,3,4-oxadiazol-2-yl)sulfanyl]-N-(2,4,6-tribromophenyl) acetamide was synthesized and the structure of synthesized compounds were determined by obtained IR, 1H NMR and Mass spectroscopy data. To evaluate biological potential of synthesized compounds they were subjected for invitro antibacterial study against gram positive bacterial strains Staphylococcus aureus, Bacillus subtilis and gram negative bacterial strains Pseudomonas aeruginosa, Escherichia coli where antibacterial potential was shown by some compounds.
Authors and Affiliations
J. P. Jadhav, Maharshi B. Shukla, Anil T. Mahato, K. A. Parmar
Keywords
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