The influence of starch hydrolysates on properties of suspensions
Journal Title: Current Issues in Pharmacy and Medical Sciences - Year 2012, Vol 25, Issue 2
Abstract
Using modified starch in suspensions is commonly practiced in food, pharmaceutical and other industries [3, 6]. The purpose of this study was to investigate the influence of starch hydrolysates, received according to our prescription, on properties of suspensions. Prepared suspensions Z01 – Z05 with PR, as the model drug, were examined for physical tests. The addition of 20 % SH2 or SH4, as suspending agent, increased the stability of preparations (0.04 cm/day and 0.05 cm/day, respectively). Drug release test according to extraction method was conducted during 24 hours. The ethanol used in acceptor medium increased the amounts of released progesterone. The received results confirm an opportunity of using starch hydrolysates as cheap and safe agents modifying physical properties of suspensions.
Authors and Affiliations
Piotr Belniak, Katarzyna Świąder, Łukasz Zimmer, Michał Szumiło, Regina Kasperek, Ewa Poleszak
Keywords
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