The Pharmacokinetics and Interactions of Ivermectin in Humans—A Mini-review
Journal Title: The AAPS Journal - Year 2008, Vol 10, Issue 1
Abstract
Ivermectin is an antiparasitic drug with a broad spectrum of activity, high efficacy as well as a wide margin of safety. Since 1987, this compound has a widespread use in veterinary medicine and it use has been extended in humans. Here we present a brief review of the information availabile regarding the pharmacokinetics and interactions of ivermectin in humans. Awareness of these characteristics could improve the clinical efficacy of Ivermectin. All Authors declare that they do not have any Conflict of interest and that the work is original. All Authors agree that the contents of the manuscript are confidential and will not be copyrighted, submitted, or published elsewhere (including the Internet), in any language, while acceptance by the Journal is under consideration.
Authors and Affiliations
Aránzazu González Canga, Ana M. Sahagún Prieto, M. José Diez Liébana, Nélida Fernández Martínez, Matilde Sierra Vega, Juan J. García Vieitez
Identification of Key Licorice Constituents Which Interact with Cytochrome P450: Evaluation by LC/MS/MS Cocktail Assay and Metabolic Profiling
The online version of this article (doi:10.1208/s12248-013-9544-9) contains supplementary material, which is available to authorized users.
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