The prediction for risk of food allergy in children with chronic Helicobacter pylori associated infection
Journal Title: Здоров`я дитини - Year 2019, Vol 14, Issue 2
Abstract
Background. Etiology and pathogenesis of food allergy in children is not completely known to the present day. The role of a number of factors, including chronic Helicobacter pylori associated infection, has been described. The purpose of the study was to identify informatively significant biomedical and socio-hygienic risk factors for the development of allergy in children with chronic Helicobacter pylori associated infection, as well as to create a mathematical model to forecast the probability of the presence or development of an allergic pathology. Materials and methods. We’ve examined 76 children aged 7 to 17 years with chronic Helicobacter pylori associated infection, who were examined and treated in the Gastroenterological Department of Dnipropetrovsk Municipal Clinical Hospital 1. Results. The risk factors were identified and a mathematical model for forecasting the development of food allergy in children with chronic Helicobacter pylori associated infection was developed. The following factors have prognostic value as the duration of the disease over 32 months, the duration of the pain syndrome over 7 days, the higher education in a child’s parent. The following endoscopic manifestations also have a significant impact: erosive focal gastritis, erosive focal bulb, ulcer on the anterior wall of the duodenum, and superficial focal duodenitis. Conclusions. The results showed that the presence of chronic Helicobacter pylori associated infection provokes the development of food allergies in children. The mathematical model of forecasting can be used in the practice of family doctors, pediatricians and pediatric gastroenterologists.
Authors and Affiliations
A. E. Lykova
Informational significance of medical and social factors that influence the health-oriented behavior of school-age children
Background. Based on medical statistics, the negative dynamics of the health status of children and adolescents in Ukraine is determined. According to the World Health Organization, lifestyle factors are a trigger of non...
Viburcol — Bioregulatory Approach in Childhood Diseases
One of the most urgent problems of modern pediatrics and neonatology is a need for drugs, which, along with proven efficacy, also will have maximal safety for a growing child’s body. This is due to pediatricians, family...
Clinical and Echocardiographic Diagnostics of Mitral Valve Prolapse Origin in Children
In order to determine hemodynamic and morphometric features of mitral valve prolapse of inflammatory and non-inflammatory origin by means of dopplerechocardiography, 34 children aged 5–17 years were examined. In children...
Features of Cellular Immunity in Children with Mono- and Mixed Rotavirus Infection
This paper presents the findings of laboratory examination in 35 infants with acute intestinal infection of rotavirus origin. The evaluation of the dynamics of cellular link of the immune system in the acute phase of the...
Expression of galectin-9 mRNA in obese children with polymorphism of the lactase gene
Background. The aim of the study is to investigate the association of expression of galectin-9 (Gal-9) mRNA and lactose malabsorption in obese children with polymorphism (SNP) of the lactase gene (LCT) and to study the e...