The Relationship among Demographic Factors, Treatment Modalities, Surgical Techniques, and Postoperative Complications in the Management of Esophageal Squamous Cell Carcinoma
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Background Surgery alone or surgery after neoadjuvant chemoradiotherapy or chemotherapy, often cause complications of varying degrees of severity. There seems to be an association between these complications and patient age, gender, as well as the treatment modalities and surgical techniques employed. This study investigated these probable relationships with regards to the current management of esophageal squamous cell carcinoma (ESCC). Methods A total of 245 ESCC patients who had received either neoadjuvant chemoradiotherapy or chemotherapy plus surgery or surgery alone, were recruited for this study. The relationships among patients’ demographic factors, treatment modalities, surgical techniques, as well as postoperative complications were analyzed. Results Two hundred and forty patients (98%) received surgery alone, 3 (1.2%) received neoadjuvant chemotherapy plus surgery, and 2 (0.8%) received neoadjuvant chemoradiotherapy plus surgery. Ivor-Lewis approach was the main surgical technique used. Pneumonia and pleural effusion were among the most frequent postoperative complications. There was a significant association between age and postoperative complications ( 2=10.194, P=0.017). Gender and postoperative complications also had a significant association ( 2=9.274, P=0.026). Neither age nor gender had a significant correlation with treatment modalities ( 2=1.297, P=0.523 and 2=1.348, P=0.510, respectively). Surgical techniques and postoperative complications had no significant relationship ( 2=9.308, P=0.409). Interpretations Age and gender are risk factors that determine the occurrence of postoperative complications. Patients can be offered any potentially good treatment irrespective of their age and gender. The surgical approach used may not be a risk factor to postoperative complications.
Authors and Affiliations
Godwin Botwe, Weifeng Tang, Michael Adu- Frimpong, Yusif M. Mukhtar
Keywords
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- EP ID EP375696
- DOI 10.9790/0853-1706026368.
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