The relationship between Osmolarity and Osmolality of Infusion Solutions of Monosaccharides
Journal Title: Journal of Pharmaceutical Sciences and Research - Year 2010, Vol 2, Issue 9
Abstract
Concentration of Osmotically active solutes plays a key role in an acceptance of parenteral infusions by patients. It is generally recommended that labels of infusions should list osmolarity (osmol/l). However, osmometer can only read osmolality (osmol/kg). The conversion of the experimental readings to the declared osmotic concentration wants to study the relationship between osmolality and osmolarity. The conversion factor defined as ratio of the solution molarity and its molality was introduced to convert osmolality to osmolarity. Unfortunately, the conversion factor changes with dilution. In this work, the total molal volume of the solute in aqueous solution, which is not influenced by the solution concentration, was used instead for aqueous solutions of monosaccharides. The method allowing estimation of the solute molal volume from its molal weight and true powder density was demonstrated. Finally, the original equation employing true density of the powder was recommended for conversion osmolality to osmolarity
Authors and Affiliations
Z. Šklubalová , Z. Zatloukal
Keywords
Related Articles
- EP ID EP85194
- DOI -
- Views 128
- Downloads 0
Elevated concentrations of plasma homocysteine in coronary artery disease patients with normal folate level.
Hyperhomocysteinemia is becoming a growing concern as a risk factor in patients suffering from coronary artery disease. The purpose of our study was to evaluate the existence of hyperhomocysteinemia with folate levels a...
Synthesis and Biological Evaluation Of Some 2-Substituted Derivatives Of Benzimidazoles
A large variety of 2-substituted benzimidazoles have been found to possess anti-inflammatory, antispasmodic, a ntihistaminic, a ntimicrobial, anticancer, c ycloxygenase inhibitor, and HIV-1 reverse transcriptase inhibit...
Oxidative Stress Bio Markers and Antioxidant Status in Cigarette Smokers Compared to Nonsmokers
Oxidative stress plays an important role in the pathogenesis of some diseases such as lung cancer, chronic obstructive pulmonary disease, and atheroscleorosis. Smoking may enhance oxidative stress not only thr...
Phytochemical and Pharmacological Screening of the Plant Crateva Magna Against Alloxan Induced Diabetes in Rats.
The plant Crateva magna belonging to family Capparaceae is used in anti spasmodic, hypotensive, anti inflammatory, hypoglycemic, anti protozoal, analgesic purposes. The present study was carried out to evaluate the eff...
Most commonly plant exposures and intoxications from outdoor toxic plants
Over the past two decades, there has been an increased recognition of the importance of wild plant used as food and as source of micronutrients and plant secondary metabolites. Non-cultivated plants are perceived as im...