To Assess the Burden of and Trends in Extra Pulmonary Tuberculosis at a Tertiary Care Hospital in India
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 8, Issue 6
Abstract
Introduction: Extra pulmonary form of tuberculosis is an important public health disease which cannot be ignored because of its low transmissibility. Data on the exact burden of the disease in developing countries is scarce. Aim: To assess the burden of the disease in a tertiary care hospital of India. To study the clinical trends in the disease, and the utility of various diagnostic modalities for its diagnosis. To identify the Mycobacterial species and perform drug susceptibility test. Materials and Methods: A cross sectional study was carried out for a period of two years. A total of one hundred and forty seven samples were tested for extrapulmonary tuberculosis using a combination of bacteriological, cytological, histological and biochemical techniques to achieve proper diagnosis of the disease. Results: Young adults and females predominated in the study group and positive cases. Microbiologically, 26% of the specimens were positive. Eighteen percent of them were found to be culture positive for M. tuberculosis. Smear by Ziehl Neelsen stain was positive in 9%. A combination of culture media both solid and liquid maximized the yield of Mycobacteria. Lymph node tuberculosis was found to be the predominant type followed by others. Fifteen percent of the strains were found to be resistant to the first line drugs used in treatment of tuberculosis. Cytology and biochemical findings were found to be less specific in diagnosis of extrapulmonary tuberculosis. Conclusion: Extrapulmonary form of tuberculosis is seen in significant number of the suspects. Hence, attention should be paid towards its proper and early diagnosis followed by rational management, as if neglected may lead to associated complications and sequalae.
Authors and Affiliations
S. Fatima, N. M. Aleemuddin, F. Fakeha
Keywords
Related Articles
- EP ID EP347321
- DOI 10.9734/BJMMR/2015/16345
- Views 77
- Downloads 0
Biobanking: A Challenge Facing Pathologists in Egypt
Background: Biobanking today plays a key tool in biomedical research. Establishment and proper running of biobanks in developing countries is confronted with a number of challenges of legal, ethical, and financial nature...
Bayesian Joint Modelling of Disease Progression Marker and Time to Death Event of HIV/AIDS Patients under ART Follow-up
Objectives: To develop separate and joint statistical models in the Bayesian framework for longitudinal measurements and time to death event data of HIV/AIDS patients. Study design: Longitudinal study. Place and Duration...
Mutations in HLA DRB1*0101 Exon 2 in a Sub-population of Latvia
Aims: To find out whether ongoing missense mutations in the exon 2 of DRB1*01:01 affect the operation of this protective allele in HIV patients. Place and Duration of Study: the Clinical Immunology and Immunogenetics Lab...
Immunological Profiles of Mice Protected from Chlamydia-induced Infertility by Anti-caspase Treatment
The study is to investigate the effect of anti-caspase treatment on anti-chlamydia immune response in mice. Both the humoral and aspects of cell-mediated immune response against Chlamydia trachomatis were studied. Antibo...
Neonatal Aerophagia Dilemma – A Gastrointestinal Functional Disorder: Role of Imaging Studies
Aerophagia is excessive swallowing of air which goes to stomach through oesophagus and causes abdominal distention. This may alert the parents of pediatric age group especially neonates and causes anxiety. Although it’s...