VALUE OF ADDING MR SPECTROSCOPY TO DYNAMIC CONTRAST-ENHANCED MR MAMMOGRAM IN EVALUATING INDETERMINATE (BIRADS 3,4) BREAST LESIONS.
Journal Title: Stanley Medical Journal - Year 2016, Vol 3, Issue 3
Abstract
Aim: The purpose of our study was to evaluate the diagnostic value of adding MR spectroscopy to dynamic contrastenhanced MRI (DCE-MRI) in patients with indeterminate breast lesions - BIRADS 3 & 4. Materials & methods: A total of 21 female patients with 27 lesions classified as BIRADS 3 & 4 by sono-mammography were examined by MRI using the multiphase dynamic sequence and proton MR spectroscopy using a high field magnet (3 Tesla). Sensitivity, specificity and accuracy for DCE-MRI, MRS and their combination were calculated and observed that combined contrast enhanced MRI with MRS had higher sensitivity, specificity and accuracy. Results & Conclusion: Adding MR spectroscopy to conventional dynamic MRI in evaluating probable and indeterminate breast lesions offered additional information that increased the sensitivity and specificity of the conventional dynamic MRI in discriminating benign and malignant lesions and thus avoiding unnecessary intervention.
Authors and Affiliations
Geetha K, Beula Emmanuel
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