Comparison of Sublingual and Vaginal Misoprostol in Cervical Ripening for First Trimester Abortion
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 10
Abstract
Abstract: To compare the effectiveness and tolerability of misoprostol as a cervical ripening agent in first trimester abortion through sublingual and vaginal administrations of administration before suction evacuation (SE).It was a hospital based comparative study. A total of 100 randomly selected married women were equally divided in two groups for sublingual (S/L) and vaginal and oral 400 mcg of misoprostol single dose administration. The drug was administered 3 hours before SE. Efficacy was assessed on the basis of dilatation achieved, duration of the procedure, intra-operative blood loss. The tolerability was noted on the basis of side effects.Statistical analysis: Mean standard deviation for descriptive analysis and Z test and Chi Square test as test of significance. The cervical dilatation in S/L and vaginal group was comparable. Total duration of the procedure in S/L group was significantly less than vaginal group (p <.0.05). The mean intra-operative blood loss was more in vaginal as compared to the S/L group (p <0.01). Abdominal pain and nausea, episodes of chills were more common with the S/L group than vaginal group.Administration of misoprostol by the sublingual administration is better than vaginal administrations for cervical ripening only disadvantage is that sublingual administration has more side effects. Keywords:Cervical ripening, first trimester abortion, misoprostol, sublingual, vaginal, comparison
Authors and Affiliations
Bhakti Shriram Maslekar, Maya Arvikar, Aarti Rapol, PadmajaShriram Maslekar, MandarDhamangaonkar angaonkar
Keywords
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