Concomitant Boost on Saturdays in Radiotherapy for Locally Advanced Oral Cavity and Oropharyngeal Cancers
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 1
Abstract
Introduction: Head and neck cancer is a major health problem in Asia, especially in the Indian subcontinent. Study aimed to assess the response of concomitant boost radiotherapy against the concurrent chemoradiotherapy in locally advanced oral cavity and oropharyngeal cancers and to compare the toxicity in terms of oral mucositis in both treatment groups. Material and methods: Total 60 patients were enrolled and randomly allotted to arm A (n=30) that received concurrent chemoradiotherapy and arm B (n=30) that received concomitant boost radiotherapy without any concurrent chemotherapy. Results: The response at 6 weeks in both treatment arms was comparable (p value- 0.721), the toxicity in terms of mucositis (p value-0.133) also came out to be comparable in both arms. Conclusion: The observations made in our study helped us arrive at a conclusion that concomitant boost radiotherapy without concomitant cisplatin has a response comparable to the conventional chemoradiotherapy regimen with not significantly higher cases of oral mucositis
Authors and Affiliations
Yashna Gupta, Pradeep Garg, Raja PS Banipal, Neeru Bedi
Keywords
Related Articles
- EP ID EP425784
- DOI -
- Views 109
- Downloads 0
Comparative Clinical Study of 0.5% Hyperbaric Bupivacaine alone and 0.5% Hyperbaric Bupivacaine with Midazolam Intrathecally for Lower Limb Orthopaedic Surgeries
Introduction: Subarachnoid blockade is the common form of central neuraxial blockade performed for lower limb orthopaedic surgeries. In order to maximize quality of anaesthesia and post-operative analgesia, a number of a...
Prevalence of Silent Coronary Artery Disease (CAD) in Asymptomatic T2DM – A Prospective Study
Introduction: To detect the coronary artery disease at an early stage and also to correlate the various risk factors (age, sex, duration of diabetes mellitus, glucose lowering drugs, FBS, PPBS, HBA1C, Lipid profile, BMI...
Endoscope-Assisted Transoral Reduction and Internal Fixation of a Mandibular Subcondylar Fracture with a 3D - Shaped Plate
Introduction: Disadvantages of open reduction of subcondylar fractures include visible facial scars and potential facial nerve damage. Endoscope-assisted procedures have solved these problems, however the anatomical adap...
Assessment of Platelet Count in Normal Kashmiri Population
Introduction: Macrothrombocytopenia, a combination of thrombocytopenia and giant platelets, can occur in a number of diseases, including chronic immune thrombocytopenia purpura and inherited giant platelet disorders. It...
Comparative Study of Outcome of Axial Continuous-Flow HeartMate II LVAD Implantation with Fully Magnetically Levitated Centrifugal Continuous-Flow HeartMate 3 LVAD for the Treatment of Advanced Heart Failure
Introduction: Left ventricular assist devices (LVAD) or assist systems, increase the rate of survival and improve quality of life among patients with advanced heart failure. So this study was done to compare the outcome...