CONTROLLED RELEASE PELLETS: AN EFFECTIVE TOOL IN CHRONIC THERAPY
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2017, Vol 7, Issue
Abstract
Abstract Multiparticulate drug delivery systems like pellets, granules, micro particles, minitablets etc., prove to be promising and highly flexible systems with ease of formulating with different drug release kinetics. In present era, pelletization technologies are gaining much attention as they represent an efficient pathway for manufacture of oral drug delivery systems. Pelletization is an agglomeration process that converts fine powders or granules of bulk drugs and excipients into small, free flowing semi-spherical units. Pellets, being multiparticulate systems, are widely used due to the technological as well as therapeutic advantages over single-unit dosage forms. The present review focus on advantages, disadvantages, formation of pellet growth, different pelletization techniques, characterization, marketed pellets products and also outlines recent developments in the pharmaceutical approaches that have been used to prepare pelletized dosage forms with different techniques emphasizing on the recent research work done in the area of pelletization.
Authors and Affiliations
R. Santosh Kumar, Mattaparthi Sahiti
Keywords
Related Articles
- EP ID EP330782
- DOI -
- Views 102
- Downloads 0
Evaluation of Lepidium sativum Mucilage as Suspending Agent in Paracetamol Suspension
Mucilages are polysaccharide complexes formed from sugar and uronic acid units. Mucilages form slimy masses in water, are typically heterogeneous in composition. The objectives of present investigation were to evaluate L...
ROLE OF HYDROPHILIC POLYMERS ON THE STABILITY OF FORMULATIONS OF TENOXICAM – SBE7-β-CD INCLUSION COMPLEX
The present study was carried out to evaluate the usefulness of sulfobutyl ether β-Cyclodextrin (SBE7-β-CD) in increasing the dissolution rate of tenoxicam. The approach employed to prepare the inclusion complexes of the...
FORMULATION AND DEVELOPMENT OF TASTE MASKED ORALLY DISINTEGRATING TABLETS (ODTS) OF CEFPODOXIME PROXETIL USING ION EXCHANGE RESINS
Urinary and respiratory tract infections are common incidences in children for which Cefpodoxime proxetil is a choice of drug .However the bitter taste of the drug limits its use, due to which conventional oral formulati...
FLOATING DRUG DELIVERY SYSTEMS: AN ALTERNATIVE APPROACH TO ENHANCE GASTRIC RESIDENCE TIME
Gastric emptying is a complex process and one of the most important obstacles in the better absorption and enhances bioavailability of oral drug delivery system. In recent years various scientific and technological advan...
PHARMACOLOGICAL PROPERTIES OF FERONIA LIMONIA FRUIT PULP – A REVIEW
Abstract Current research on drug development has emphasized on traditional uses of herbal constituents which were practiced in ancient times. Many parts of Feronia limonia were prescribed for diseases in ancient medicin...