Depression associated with cardiac surgery and the probable risk factors- A randomised observational clinical study
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2016, Vol 20, Issue 1
Abstract
Introduction: Cardiovascular surgery can trigger depression; counselling and medications can easily beat it. The earlier we identify people who have depression, complicating their ability to get back to normal life, better is the chances of recovery. We conducted a prospective randomized observational study to assess incidence of depression in patients undergoing cardiac surgery and risk factors which can trigger depression. Materials and Methods: A prospective randomized double blind controlled Observational clinical study was conducted in 250 patients who underwent open heart surgery with and without assistance of cardio pulmonary bypass (CPB) from May 2013 to July 2014. All patients were screened for depression with Patient Health Questionnaire (PHQ-9) preoperatively (Q1), at hospital discharge (Q2), 3months (Q3) and 6months (Q4) postoperatively. At each interval patients were identified as ‘‘not depressed’’ (PHQ-9 score 0), minimally depressed (score 1-4), mild(score5-9), moderate (10-14), moderately severe(15-19), severe depression(20-27). Multiple regression analysis was used to identify variables associated with depression. Results: On regression analysis, preoperative depression for depression at discharge (OR 88.5, p<0.0001), depression at discharge for incidence of depression at three months (OR 4004, p<0.0001) and 6 months (OR 1194, p<0.0001) had significant Odds ratio (OR) with statistical significance. Patients who had depression at discharge were older, had lower preoperative ejection fraction (EF), prolonged waiting period, ICU stay, hospital stay. Other risk factors identified were higher NYHA class , history of prior CCF, abnormal lipid profile, pre-existing hypertension, diabetes mellitus, peripheral vascular disease and patients on beta blockers. Conclusion: Depression is common after cardiac surgery. Among all the risk factors, preoperative depression was associated with the highest risk for postoperative depression.
Authors and Affiliations
K R Davan, Bindu . , Mallikarjuna . , Sowmia Mammen, Sumaiya Sabreen
Keywords
Related Articles
- EP ID EP496854
- DOI -
- Views 86
- Downloads 0
Cost analysis of different brands of anxiolytic and sedative-hypnotic drugs available in India
Background: Significant proportion of population suffers from anxiety and sleep disorders. Sedative-hypnotics are one of the most commonly prescribed classes of psychotropic drugs. Cost of treatment can determine complia...
Retrospective Study of Eclampsia in a Teaching Hospital
Eclampsia is one of the major cause of both maternal and perinatal mortality in India. Retrospective study of eclampsia was done in our hospital from Jan-2011 to Jun-2013 Over a period of 2 ½ year to know the incidence,...
Eradicating bacteria with silica and polyethylene glycolcoated gold nanoparticles using photothermal therapy
Various species of bacteria have adapted to manmade chemicals and antibiotics, developing into superbugs posing a threat to humankind, and soon creating a future where antibiotics are futile against various diseases. In...
In-Vitro cultivation of mycobacterium leprae and confirmation by molecular method
In-Vitro cultivation of mycobacterium leprae and confirmation by molecular method
Mortality Pattern of Hospitalized Neonates in Government Medical College and Hospital, Latur, Maharashtra
Background: Records of vital events like death constitute an important component of Health Information System. Mortality data from hospitalized patients reflect the causes of major illnesses and care-seeking behavior of...