Evaluation of serum uric acid in type two diabetic nephropathy patients

Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 4

Abstract

Introduction Diabetic nephropathy is one of the leading complications of longstanding diabetes mellitus With the background of inflammation there is need for laboratory tests for early diagnosis and prevention of diabetic nephropathyMaterials and Methods A cross sectional study done after screening patients satisfying the inclusion and exclusion criteria 50 patients of type II diabetic patients with nephropathy Group I and 50 type II diabetic patients without nephropathyGroup II were included in the study Serum uric acid was estimated by standard enzymatic uricase method on autoanalyser ADVIA 1800 Serum urea was estimated by urease method and serum creatinine was estimated by Jaffes method and SrUric Acid by uricase method using fully autoanalyzer ADVIA 1800Results The mean age in group I was 59 928 years and group II was 562 1147 years The serum Uric Acid was 951 246 mgdl in group I and statistically significant p 168 mgdl The Serum creatinine in group I 668 294 mgdl and statistically significant p 077 mgdl There was positive correlation between SrUric Acid and Sr Creatinine r0625 pConclusion Regular detection can help the clinician to take appropriate action to delay complications which in turn may help preserve renal function in DN patientsKeywords Creatinine Urea Fasting blood glucose Urine albumin

Authors and Affiliations

Guha Niyogi NI, Baviskar P. A, V W Patil, Bagle T. R

Keywords

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  • EP ID EP475443
  • DOI 10.18231/2394-6377.2018.0129
  • Views 69
  • Downloads 0

How To Cite

Guha Niyogi NI, Baviskar P. A, V W Patil, Bagle T. R (2018). Evaluation of serum uric acid in type two diabetic nephropathy patients. International Journal of Clinical Biochemistry and Research, 5(4), 608-612. https://europub.co.uk./articles/-A-475443