Identification and evaluation of antimicrobial properties in the extract of vallaris Solanacea.
Journal Title: Journal of Medical Science and Technology - Year 2015, Vol 4, Issue 2
Abstract
The emergence and spread of multidrug resistant bacterial pathogens have substantially threatened the current antibacterial therapy, warranting the search for other alternatives. New antibacterial treatments are urgently needed. India is one of the twelve mega biodiversity centers having more than 45,000 plant species. A vast ethnobotanical lore exists in India from ancient time which can be of real use in the formulation of effective antimicrobials. Herbal world is continuously explored for natural therapeutics. In this paper a discussion is made on antimicrobial properties of plants. Evaluation of antibacterial properties of Vallaris solanacea was done. Anti bacterial activity of methanolic extracts of Vallaris solanacea was screened by agar disc diffusion method. The evaluated plant extract was found to exert a range of in vitro growth inhibitory action against the tested bacterial species, namely gram positive bacteria (Staphylococcus aureus) and gram negative bacteria (Escherichia coli). Plant extract displayed a potential antibacterial activity with MIC 100.0 μg/ml. To understand the mechanism of antimicrobial action, inhibition analysis of plant extract with para chloro mercury benzoate showed it was a cysteine protease.
Authors and Affiliations
Somavarapu Silpa, Nallabothula Mallikarjuna Rao
Keywords
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