Impact comparison between Voluven and Hartmann’s solutions administered before anesthesia on blood glucose level induced by general anesthesia and surgery
Journal Title: Journal of Medical Science and Technology - Year 2016, Vol 5, Issue 1
Abstract
To assess the effects of preoperative administration of Hartmann’s and Voluven 6% solutions on perioperative blood glucose level during general anesthesia and surgery. Our prospective, randomized and double-blind study included 126 patients, of both sexes, aged 34-52years, classed I physical status by the American society of anesthesiologists (ASA) and scheduled for various elective intermediate type of surgical interventions performed under general anesthesia at Prince Hashem bin Abdullah the second hospital, Aqaba, Jordan, during the period Dec.2012-Oct.2014. Patients were divided into three groups in a random fashion according to the preoperative administered solution. Group I patients (n=43) received preoperative Voluven 6% solution (hydroxethyl starch) with infusion rate of 10 ml/kg body weight/hour during 30 minutes, group II patients (n=41) received preoperative Hartmann’s solution (compound sodium lactate) with infusion rate of 10 ml/kg body weight/hour during 30 minutes and group III patients (n=42) received preoperative normal saline 0.9% with infusion rate of 10 ml/kg body weight/hour during 30 minutes. Blood glucose readings were recorded before solution administration (0h, I), at the end of solution administration (0h, II) and at ½ h intervals during 2hours of general anesthesia. Analysis of variance test was used to test statistical significance and P<0.05 was considered significant. The Hartmann’s and Voluven solutions increased significantly the perioperative blood glucose levels compared to Normal saline (P<0.05). Voluven increased significantly perioperative blood glucose level compared to Hartmann’s solution (P<0.05). Voluven 6% and Hartmann’s solutions produce a significant increase in perioperative blood glucose levels.
Authors and Affiliations
Hani Awad Rwashdeh
Keywords
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