Retrospective Evaluation of Impact of Radio Contrast Enhanced Computed Tomography of the Renal System in Diabetic Patients: A Comparative Study
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
Background: In the field of imaging and diagnosis, Contrast media (CM) are becoming increasingly used. This results in the rising incidence of iatrogenic renal function impairment caused by the exposure to CM, a condition known as contrast induced nephropathy (CIN). There has been increase in usage of contrast media and computed tomography (CT) scan of renal system in diabetic patients. Hence; we planned the present study to assess the effect of radio contrast enhanced CT of renal system in diabetic patients and compare it with non-diabetic subjects. Materials & Methods: The present study included retrospective assessment of effect of radio contrast enhanced CT of renal system in diabetic and non-diabetic subjects. A total of 40 subjects were included in the present study, out of which 20 were diabetic and 20 were non- diabetic. Patient details were obtained from the archives of the data records of the department of radio-diagnosis. Investigation records of all the patients were obtained for the assessment of contrast induced nephropathy and before the procedure blood urea levels and serum creatinine levels were measured. Data records of repeat creatinine and creatinine clearance post-procedure after 48 hours were obtained and assessed. All the results were assessed by SPSS software. Results: A total of 40 patients were included in the present study. Mean pre-operative and post-operative value of plasma creatinine levels in non-diabetic patients was 0.75 and 0.95 mg/dl respectively. In the diabetic group, mean pre-operative and post-operative value of plasma creatinine levels was 0.79 and 1.10 mg/dl respectively. Significant results were obtained while comparing the preoperative and postoperative mean plasma creatinine values in both the study groups. No-significant results were obtained while comparing the mean post-operative plasma creatinine values in between both the study groups. Conclusion: Transient increase in plasma creatinine of all patients does occur while utilizing the contrast medium in all patients.
Authors and Affiliations
Apurva Vohra
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