Safety And Efficacy of Unani Compound Drug in Helicobacter Pylori Positive Antral Gastritis (Warm-E-Meda Patients): A Controlled Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 9
Abstract
Warm-e-meda/gastritis is the prime concern in unani medicine and unani physicians emphasized on better functioning of stomach/meda. Acute gastritis, chronic gastritis, peptic ulcer disease, atrophic gastritis, gastric carcinoma, primary gastric B-cell lymphoma are some of the manifestation of H. pylori infection. An appreciable number of unani mufrad (single) and murakkab (compound) drugs are used to treat them. In this study we evaluate the efficacy of a unani compound drug in endoscopically proved H.pylori positive antral gastritis. This was a double blind randomised clinical trial, on 160 patients. All the patients were divided into three groups. Test group comprising of 110 patients, control group comprised of 20 patients and placebo group comprising 30 patients. Patients of control group were given tab Pantoprazole (40 mg). All the drugs were given for a period of 3 months and weekly follow up was done and repeat endoscopy was carried out after completion of treatment. In 84.5% patients H. Pylori positive antral gastritis was found in group A (test group), 66.7% in group B (Placebo group) and 100% in group C (control group). Antral gastritis was cured in 89.1% patients in group A (test group), only 3.3% in group B and 40% in group C. 90% patients became H. Pylori negative after receiving test drug for 3 months, only 6.7% patients became negative in group B while in group C all the patients remained H. Pylori positive after treatment. In our study we found the Unani polyherbal formulation was found to be effective in treating antral gastritis and eradicating H. Pylori bacteria
Authors and Affiliations
Rahida Hilal, Mehjabeen Fatimah, Anis Ismail, Iqbal Aziz, Tafseer Ali
Keywords
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- EP ID EP255787
- DOI 10.9790/0853-1609028188
- Views 65
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