Sirs Scoring And Interleukin 6 on Admission As Prognostic Indicators in Severe Acute Pancreatitis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Acute pancreatitis being one of the diseases with varied prognosis due to its varied severity, poses a great difficulty in diagnosis and appropriate management. There are no test and scoring systems that hold significance in the initial 24 hours of the onset of the disease which could indicate the prognosis of the disease. So our study involves using SIRS scoring and IL-6 as prognostic indicators in severe acute pancreatitis. Methods: SIRS scoring system and serum concentration of IL -6 was evaluated for 30 patients with diagnosis of acute pancreatitis at time of admission.These 30 patients were divided into 2 groups- mild and severe pancreatitis depending on presence of organ failure and/or local complications such as necrosis, abscess or pseudocyst. Correlation between sirs score and IL-6 levels and its role in predicting severity of pancreatitis was evaluated Result: SIRS score for severe form was more than 2 while mild form had score < 2. Serum concentrations of IL-6 was highly significantly different between the severe group and the mild group on the day of admission. Even SIRS score and IL-6 levels showed significant correlation with severity pancreatitis.
Authors and Affiliations
Dr. Dharamdev D, Dr. Pruthviraj A S
Keywords
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- EP ID EP244068
- DOI 10.9790/0853-1610070811
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